An efficient system for the evolution of aminoacyl-tRNA
synthetase specificity. Santoro, Stephen W.; Wang, Lei; Herberich,
Brad; King, David S.; Schultz, Peter G.. Departments of Chemistry,
The Scripps Research Institute, Skaggs Institute for Chemical Biology,
La Jolla, CA, USA. Nature Biotechnology (2002), 20(10), 1044-1048.
Structural genomics of the Thermotoga maritima proteome
implemented in a high-throughput structure determination pipeline. Lesley,
Scott A.; Kuhn, Peter; Godzik, Adam; Deacon, Ashley M.; Mathews,
Irimpan; Kreusch, Andreas; Spraggon, Glen; Klock, Heath E.; McMullan,
Daniel; Shin, Tanya; Vincent, Juli; Robb, Alyssa; Brinen, Linda
S.; Miller, Mitchell D.; McPhillips, Timothy M.; Miller, Mark A.;
Scheibe, Daniel; Canaves, Jaume M.; Guda, Chittibabu; Jaroszewski,
Lukasz; Selby, Thomas L.; Elsliger, Marc-Andre; Wooley, John; Taylor,
Susan S.; Hodgson, Keith O.; Wilson, Ian A.; Schultz, Peter G.;
Stevens, Raymond C. Joint Center for Structural Genomics, Genomics
Institute of the Novartis Research Foundation, San Diego, CA, USA.
Proceedings of the National Academy of Sciences of the United States
of America (2002), 99(18), 11664-11669.
Purine-based inhibitors of inositol-1,4,5-trisphosphate-3-kinase. Chang,
Young-Tae; Choi, Gildon; Bae, Yoe-Sik; Burdett, Matthew; Moon, Ho-Sang;
Lee, Jae Wook; Gray, Nathanael S.; Schultz, Peter G.; Meijer, Laurent;
Chung, Sung-Kee; Choi, Kwan Yong; Suh, Pann-Ghill; Ryu, Sung Ho.
Department of Chemistry, New York University, New York, NY, USA.
ChemBioChem (2002), 3(9), 897-901.
"Development of a Genetic Selection for Catalytic
Antibodies" [Bioorg. Med. Chem. Lett. 12 (2002) 1691].
Gildersleeve, Jeff; Janes, Jeff; Ulrich, Helle; Yang, Priscilla;
Barbas, Carlos; Schultz, Peter G.. Department of Chemistry, The
Scripps Research Institute, La Jolla, CA, USA. Bioorganic & Medicinal
Chemistry Letters (2002), 12(19), 2789.
Gene expression during the priming phase of liver
regeneration after partial hepatectomy in mice. Su, Andrew
I.; Guidotti, Luca G.; Pezacki, John Paul; Chisari, Francis V.;
Schultz, Peter G.. Department of Chemistry and Molecular and Experimental
Medicine, The Scripps Research Institute, La Jolla, CA, USA. Proceedings
of the National Academy of Sciences of the United States of America
(2002), 99(17), 11181-11186.
Profiling protein function with small molecule microarrays. Winssinger,
Nicolas; Ficarro, Scott; Schultz, Peter G.; Harris, Jennifer L. Genomics
Institute of the Novartis Research Foundation, San Diego, CA, USA.
Proceedings of the National Academy of Sciences of the United States
of America (2002), 99(17), 11139-11144.
Addition of a photocrosslinking amino acid to the
genetic code of escherichia coli. Chin, Jason W.; Martin, Andrew
B.; King, David S.; Wang, Lei; Schultz, Peter G.. Department of
Chemistry and The Skaggs Institute for Chemical Biology, The Scripps
Research Institute, La Jolla, CA, USA. Proceedings of the National
Academy of Sciences of the United States of America (2002), 99(17),
11020-11024.
The selective incorporation of alkenes into proteins
in escherichia coli. Zhang, Zhiwen; Wang, Lei; Brock, Ansgar;
Schultz, Peter G.. Department of Chemistry, The Scripps Research
Institute, La Jolla, CA, USA. Angewandte Chemie, International
Edition (2002), 41(15), 2840-2842.
Comparative Analysis of Human Genome Assemblies
Reveals Genome-Level Differences. Li, Shuyu; Liao, Jiayu; Cutler,
Gene; Hoey, Timothy; Hogenesch, John B.; Cooke, Michael P.; Schultz,
Peter G.; Ling, Xuefeng Bruce. Tularik, Inc., South San Francisco,
CA, USA. Genomics (2002), 80(2), 138-139.
Antibody catalysis: Completing the circle. Schultz,
P. G.; Lerner, R. A. Department of Chemistry, Scripps Research Institute,
La Jolla, CA, USA. Nature (London, United Kingdom) (2002), 418(6897),
485.
Genomic Effects of Polyamide/DNA Interactions on
mRNA Expression. Supekova, Lubica; Pezacki, John Paul; Su,
Andrew I.; Loweth, Colin J.; Riedl, Rainer; Geierstanger, Bernhard;
Schultz, Peter G.; Wemmer, David E. Department of Chemistry, The
Scripps Research Institute, La Jolla, CA, USA. Chemistry & Biology
(2002), 9(7), 821-827.
Addition of p-Azido-L-phenylalanine to the Genetic
Code of Escherichia coli. Chin, Jason W.; Santoro, Stephen
W.; Martin, Andrew B.; King, David S.; Wang, Lei; Schultz, Peter
G.. Department of Chemistry and the Skaggs Institute for Chemical
Biology, The Scripps Research Institute, La Jolla, CA, USA. Journal
of the American Chemical Society (2002), 124(31), 9026-9027.
Towards the generation of artificial O6-alkylguanine-DNA
alkyltransferases: In vitro selection of antibodies with reactive
cysteine residues. Damoiseaux, Robert; Schultz, Peter G.; Johnsson,
Kai. Institute of Molecular and Biological Chemistry, Swiss Federal
Institute of Technology Lausanne, lausanne, Switz. ChemBioChem
(2002), 3(6), 573-575.
Development of a genetic selection for catalytic
antibodies. Gildersleeve, Jeff; Janes, Jeff; Ulrich, Helle;
Yang, Priscilla; Barbas, Carlos; Schultz, Peter G.. Department
of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Bioorganic & Medicinal Chemistry Letters (2002), 12(12), 1691-1694.
Directed evolution of novel polymerase activities:
mutation of a DNA polymerase into an efficient RNA polymerase. Xia,
Gang; Chen, Liangjing; Sera, Takashi; Fa, Ming; Schultz, Peter
G.; Romesberg, Floyd E. Department of Chemistry, The Scripps Research
Institute, La Jolla, CA, USA. Proceedings of the National Academy
of Sciences of the United States of America (2002), 99(10), 6597-6602.
Coordinated transcription of key pathways in the
mouse by the circadian clock. Panda, Satchidananda; Antoch,
Marina P.; Miller, Brooke H.; Su, Andrew I.; Schook, Andrew B.;
Straume, Marty; Schultz, Peter G.; Kay, Steve A.; Takahashi, Joseph
S.; Hogenesch, John B. The Genomics Institute of the Novartis Research
Foundation, San Diego, CA, USA. Cell (Cambridge, MA, United States)
(2002), 109(3), 307-320.
Inhibition and Reversal of Myogenic Differentiation
by Purine-Based Microtubule Assembly Inhibitors. Perez, Omar
D.; Chang, Young-Tae; Rosania, Gustavo; Sutherlin, Dan; Schultz,
Peter G.. Department of Chemistry, University of California, Berkeley,
Berkeley, CA, USA. Chemistry & Biology (2002), 9(4), 475-483.
Large-scale analysis of the human and mouse transcriptomes. Su,
Andrew I.; Cooke, Michael P.; Ching, Keith A.; Hakak, Yaron; Walker,
John R.; Wiltshire, Tim; Orth, Anthony P.; Vega, Raquel G.; Sapinoso,
Lisa M.; Moqrich, Aziz; Patapoutian, Ardem; Hampton, Garret M.; Schultz,
Peter G.; Hogenesch, John B. Department of Chemistry and Cell Biology,
The Scripps Research Institute, La Jolla, CA, USA. Proceedings of
the National Academy of Sciences of the United States of America
(2002), 99(7), 4465-4470.
Directed evolution of the site specificity of Cre
recombinase. Santoro, Stephen W.; Schultz, Peter G.. Department
of Chemistry and the Skaggs Institute for Chemical Biology, The
Scripps Research Institute, La Jolla, CA, USA. Proceedings of the
National Academy of Sciences of the United States of America (2002),
99(7), 4185-4190.
An approach to rapid protein crystallization using
nanodroplets. Santarsiero, B. D.; Yegian, D. T.; Lee, C. C.;
Spraggon, G.; Gu, J.; Scheibe, D.; Uber, D. C.; Cornell, E. W.;
Nordmeyer, R. A.; Kolbe, W. F.; Jin, J.; Jones, A. L.; Jaklevic,
J. M.; Schultz, P. G.; Stevens, R. C. Genomics Institute of the
Novartis Research Foundation, San Diego, CA, USA. Journal of Applied
Crystallography (2002), 35(2), 278-281.
Transcriptional Effects of the Potent Enediyne Anti-Cancer
Agent Calicheamicin γ1I. Watanabe, Coran M. H.; Supekova,
Lubica; Schultz, Peter G.. Department of Chemistry, The Scripps
Research Institute, La Jolla, CA, USA. Chemistry & Biology
(2002), 9(2), 245-251.
Exploring the Limits of Codon and Anticodon Size. Anderson,
J. Christopher; Magliery, Thomas J.; Schultz, Peter G.. Department
of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Chemistry & Biology (2002), 9(2), 237-244.
Adding L-3-(2-Naphthyl)alanine to the genetic code
of Escherichia coli. Wang, Lei; Brock, Ansgar; Schultz, Peter
G.. Department of Chemistry, University of California at Berkeley,
Berkeley, CA, USA. Journal of the American Chemical Society (2002),
124(9), 1836-1837.
The Synthesis and Biological Characterization of
a Ceramide Library. Chang, Young-Tae; Choi, Jaehwa; Ding, Sheng;
Prieschl, Eva E.; Baumruker, Thomas; Lee, Jae-Mok; Chung, Sung-Kee;
Schultz, Peter G.. Department of Chemistry, The Scripps Research
Institute, San Diego, CA, USA. Journal of the American Chemical
Society (2002), 124(9), 1856-1857.
A Combinatorial Scaffold Approach toward Kinase-Directed
Heterocycle Libraries. Ding, Sheng; Gray, Nathanael S.; Wu,
Xu; Ding, Qiang; Schultz, Peter G.. Department of Chemistry and
the Skaggs Institute for Chemical Biology, The Scripps Research
Institute, La Jolla, CA, USA. Journal of the American Chemical
Society (2002), 124(8), 1594-1596.
IN02, a positive regulator of lipid biosynthesis,
is essential for the formation of inducible membranes in yeast. Block-Alper,
Laura; Webster, Paul; Zhou, Xianghong; Supekova, Lubica; Wong,
Wing Hung; Schultz, Peter G.; Meyer, David I. Department of Biological
Chemistry, University of California Los Angeles School of Medicine,
Los Angeles, CA, USA. Molecular Biology of the Cell (2002), 13(1),
40-51.
Resin-Capture and Release Strategy toward Combinatorial
Libraries of 2,6,9-Substituted Purines. Ding, Sheng; Gray,
Nathanael S.; Ding, Qiang; Wu, Xu; Schultz, Peter G.. Department
of Chemistry, Skaggs Institute for Chemical Biology, The Scripps
Research Institute, La Jolla, CA, USA. Journal of Combinatorial
Chemistry (2002), 4(2), 183-186.
Expanding the genetic code. Wang, Lei; Schultz,
Peter G.. Department of Chemistry, University of California at Berkeley,
Berkeley, CA, USA. Chemical Communications (Cambridge, United Kingdom)
(2002), (1), 1-11.
Generating new molecular function: a lesson from
nature. Liu, David R.; Schultz, Peter G.. Howard Hughes Medical
Institute and Department of Chemistry, University of California,
Berkeley, CA, USA. Editor(s): Quinkert, Gerhard; Kisakuerek, M.
Volkan. Essays in Contemporary Chemistry (2001), 341-379. Publisher:
Verlag Helvetica Chimica Acta, Zurich, Switz.
Phage-display evolution of tyrosine kinases with
altered nucleotide specificity. Ting, Alice Y.; Witte, Krista;
Shah, Kavita; Kraybill, Brian; Shokat, Kevan M.; Schultz, Peter
G.. Department of Chemistry, The Scripps Research Institute, La
Jolla, CA, USA. Biopolymers (2001), 60(3), 220-228.
Expanding the diversity of purine libraries. Ding,
Sheng; Gray, Nathanael S.; Ding, Qiang; Schultz, Peter G.. The Scripps
Research Institute, Department of Chemistry and the Skaggs Institute
for Chemical Biology, La Jolla, CA, USA. Tetrahedron Letters (2001),
42(50), 8751-8755.
Synthesis and biological evaluation of myoseverin
derivatives: microtubule assembly inhibitors. Chang, Young-Tae;
Wignall, Sarah M.; Rosania, Gustavo R.; Gray, Nathanael S.; Hanson,
Sarah R.; Su, Andrew I.; Merlie, John, Jr.; Moon, Ho-Sang; Sangankar,
Sameep B.; Perez, Omar; Heald, Rebecca; Schultz, Peter G.. Department
of Chemistry, New York University, New York, NY, USA. Journal of
Medicinal Chemistry (2001), 44(26), 4497-4500.
Structure of a Copper-Mediated Base Pair in DNA. Atwell,
Shane; Meggers, Eric; Spraggon, Glen; Schultz, Peter G.. Department
of Chemistry, Scripps Research Institute, La Jolla, CA, USA. Journal
of the American Chemical Society (2001), 123(49), 12364-12367.
Design of allele-specific protein methyltransferase
inhibitors. Lin, Qing; Jiang, Fanyi; Schultz, Peter G.; Gray,
Nathanael S. Department of Chemistry and Skaggs Institute for Chemical
Biology, The Scripps Research Institute, La Jolla, CA, USA. Journal
of the American Chemical Society (2001), 123(47), 11608-11613.
Molecular classification of human carcinomas by
use of gene expression signatures. Su, Andrew I.; Welsh, John
B.; Sapinoso, Lisa M.; Kern, Suzanne G.; Dimitrov, Petre; Lapp,
Hilmar; Schultz, Peter G.; Powell, Steven M.; Moskaluk, Christopher
A.; Frierson, Henry F., Jr.; Hampton, Garret M. Department of Chemistry,
The Scripps Research Institute, La Jolla, CA, USA. Cancer Research
(2001), 61(20), 7388-7393.
Solid-Phase Synthesis of 2,3,5-Trisubstituted Indoles. Wu,
Tom Y. H.; Ding, Sheng; Gray, Nathanael S.; Schultz, Peter G.. Department
of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps
Research Institute, La Jolla, CA, USA. Organic Letters (2001), 3(24),
3827-3830.
A Concise and Traceless Linker Strategy toward Combinatorial
Libraries of 2,6,9-Substituted Purines. Ding, Sheng; Gray,
Nathanael S.; Ding, Qiang; Schultz, Peter G.. Department of Chemistry
and the Skaggs Institute for Chemical Biology, The Scripps Research
Institute, La Jolla, CA, USA. Journal of Organic Chemistry (2001),
66(24), 8273-8276.
Functionalized xenon as a biosensor. Spence,
Megan M.; Rubin, Seth M.; Dimitrov, Ivan E.; Ruiz, E. Janette; Wemmer,
David E.; Pines, Alexander; Yao, Shao Qin; Tian, Feng; Schultz, Peter
G.. Department of Chemistry, University of California, Berkeley,
CA, USA. Proceedings of the National Academy of Sciences of the United
States of America (2001), 98(19), 10654-10657.
From split-pool libraries to spatially addressable
microarrays and its application to functional proteomic profiling. Winssinger,
Nicolas; Harris, Jennifer L.; Backes, Bradley J.; Schultz, Peter
G.. Department of Chemistry and the Skaggs Institute for Chemical
Biology, The Scripps Research Institute, La Jolla, CA, USA. Angewandte
Chemie, International Edition (2001), 40(17), 3152-3155.
A general approach for the generation of orthogonal
tRNAs. Wang, L.; Schultz, P. G.. Dep. Chem., Univ. California
at Berkeley, Berkeley, CA, USA. Chemistry & Biology (2001),
8(9), 883-890.
Phage selection for site-specific incorporation
of unnatural amino acids into proteins in vivo. Pastrnak, M.;
Schultz, P. G.. Department of Molecular and Cell Biology, University
of California, Berkeley, CA, USA. Bioorganic & Medicinal Chemistry
(2001), 9(9), 2373-2379.
A comparison of the Celera and Ensembl predicted
gene sets reveals little overlap in novel genes. Hogenesch,
J. B.; Ching, K. A.; Batalov, S.; Su, A. I.; Walker, J. R.; Zhou,
Y.; Kay, S. A.; Schultz, P. G.; Cooke, M. P. Genomics Inst. Novartis
Res. Found., san Diego, CA, USA. Cell (Cambridge, MA, United States)
(2001), 106(4), 413-415.
Development of synthetic viroids. Zhou, Demin;
Schultz, Peter G.. Chemistry, The Scripps Research Institute, La
Jolla, CA, USA. Abstracts of Papers, 222nd ACS National Meeting,
Chicago, IL, United States, August 26-30, 2001 (2001), BIOL-194.
Publisher: American Chemical Society, Washington, D. C.
A Comparative Analysis of the Immunological Evolution
of Antibody 28B4. Yin, Jun; Mundorff, Emily C.; Yang, Priscilla
L.; Wendt, K. Ulrich; Hanway, Denise; Stevens, Raymond C.; Schultz,
Peter G.. Department of Chemistry and Molecular Biology, Scripps
Research Institute, La Jolla, CA, USA. Biochemistry (2001), 40(36),
10764-10773.
Genome-wide gene expression profiles of the developing
mouse hippocampus. Mody, Monica; Cao, Yanxiang; Cui, Zhenzhong;
Tay, Khoon-Yen; Shyong, Andy; Shimizu, Eiji; Pham, Kelvin; Schultz,
Peter; Welsh, Douglas; Tsien, Joe Z. Department of Molecular Biology,
Princeton University, Princeton, NJ, USA. Proceedings of the National
Academy of Sciences of the United States of America (2001), 98(15),
8862-8867.
Discovery of estrogen sulfotransferase inhibitors
from a purine library screen. Verdugo, Dawn E.; Cancilla, Mark
T.; Ge, Xue; Gray, Nathanael S.; Chang, Young-Tae; Schultz, Peter
G.; Negishi, Masahiko; Leary, Julie A.; Bertozzi, Carolyn R. Departments
of Chemistry and Molecular and Cell Biology, University of California,
Berkeley, CA, USA. Journal of Medicinal Chemistry (2001), 44(17),
2683-2686.
Efforts toward Expansion of the Genetic Alphabet:
Replication of DNA with Three Base Pairs. Tae, Eunju Lee; Wu,
Yiqin; Xia, Gang; Schultz, Peter G.; Romesberg, Floyd E. Department
of Chemistry, Scripps Research Institute, La Jolla, CA, USA. Journal
of the American Chemical Society (2001), 123(30), 7439-7440.
Ratiometric single-molecule studies of freely diffusing
biomolecules. Deniz, Ashok A.; Laurence, Ted A.; Dahan, Maxime;
Chemla, Daniel S.; Schultz, Peter G.; Weiss, Shimon. Department
of Chemistry, The Skaggs Institute for Chemical Biology, The Scripps
Research Institute, La Jolla, CA, USA. Annual Review of Physical
Chemistry (2001), 52 233-253.
The in vivo neuromodulatory effects of the herbal
medicine Ginkgo biloba. Watanabe, Coran M. H.; Wolffram, Siegfried;
Ader, Peter; Rimbach, Gerald; Packer, Lester; Maguire, John J.;
Schultz, Peter G.; Gohil, Kishorchandra. Department of Chemistry,
Scripps Research Institute, La Jolla, CA, USA. Proceedings of the
National Academy of Sciences of the United States of America (2001),
98(12), 6577-6580.
Expanding the genetic code of Escherichia coli. Wang,
Lei; Brock, Ansgar; Herberich, Brad; Schultz, Peter G.. Department
of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps
Research Institute, La Jolla, CA, USA. Science (Washington, DC, United
States) (2001), 292(5516), 498-500.
Monitoring the Conformational Fluctuations of DNA
Hairpins Using Single-Pair Fluorescence Resonance Energy Transfer. Grunwell,
Jocelyn R.; Glass, Jennifer L.; Lacoste, Thilo D.; Deniz, Ashok
A.; Chemla, Daniel S.; Schultz, Peter G.. Departments of Chemistry
and Physics, University of California, Berkeley, CA, USA. Journal
of the American Chemical Society (2001), 123(18), 4295-4303.
Expanding the Genetic Code: Selection of Efficient
Suppressors of Four-base Codons and Identification of "Shifty" Four-base
Codons with a Library Approach in Escherichia coli. Magliery,
Thomas J.; Anderson, J. Christopher; Schultz, Peter G.. Department
of Chemistry, University of California, Berkeley, CA, USA. Journal
of Molecular Biology (2001), 307(3), 755-769.
Functional molecules: A lesson from nature. Schultz,
Peter. Department of Chemistry, CVN 22, Scripps Research Institute,
La Jolla, CA, USA. Abstr. Pap. - Am. Chem. Soc. (2001), 221st POLY-144.
Functional molecules: A lesson from Nature. Schultz,
Peter G.. Department of Chemistry, The Scripps Research Institute,
La Jolla, CA, USA. Abstr. Pap. - Am. Chem. Soc. (2001), 221st ORGN-228.
Integrated approach to gene function. Schultz,
Peter G.. The Genomics Institute of the Novartis Research Foundation,
San Diego, CA, USA. Abstr. Pap. - Am. Chem. Soc. (2001), 221st BTEC-046.
Probing ion permeation and gating in a K+ channel
with backbone mutations in the selectivity filter. Lu, Tao;
Ting, Alice Y.; Mainland, Joel; Jan, Lily Y.; Schultz, Peter G.;
Yang, Jian. Department of Biological Sciences, Columbia University,
New York, NY, USA. Nature Neuroscience (2001), 4(3), 239-246.
The effects of aging on gene expression in the hypothalamus
and cortex of mice. Jiang, Cecilia H.; Tsien, Joe Z.; Schultz,
Peter G.; Hu, Yinghe. Genomics Institute of the Novartis Research
Foundation, San Diego, CA, USA. Proceedings of the National Academy
of Sciences of the United States of America (2001), 98(4), 1930-1934.
The Harvey Lectures, Series 94. Davis, Mark
M.; Fuchs, Elaine; Hunger, Tony; Jan, Lily Yeh; Jan, Yuh Nung; Schultz,
Peter G.; Sigler, Paul B.; Weatherall, D. J.; Editors. USA. (2000),
159 pp. Publisher: (Wiley-Liss, New York, N. Y.) Book written in
English.
Effects of environmental enrichment on gene expression
in the brain. Rampon, Claire; Jiang, Cecilia H.; Dong, Helin;
Tang, Ya-Ping; Lockhart, David J.; Schultz, Peter G.; Tsien, Joe
Z.; Hu, Yinghe. Genomics Institute of the Novartis Research Foundation,
San Diego, CA, USA. Proceedings of the National Academy of Sciences
of the United States of America (2000), 97(23), 12880-12884.
Misregulation of gene expression in primary fibroblasts
lacking poly(ADP-ribose) polymerase. Simbulan-Rosenthal, Cynthia
M.; Ly, Danith H.; Rosenthal, Dean S.; Konopka, Genevieve; Luo,
RuiBai; Wang, Zhao-Qi; Schultz, Peter G.; Smulson, Mark E. Department
of Biochemistry and Molecular Biology, Georgetown University School
of Medicine, Washington, DC, USA. Proceedings of the National Academy
of Sciences of the United States of America (2000), 97(21), 11274-11279.
A new orthogonal suppressor tRNA/aminoacyl-tRNA
synthetase pair for evolving an organism with an expanded genetic
code. Pastrnak, Miro; Magliery, Thomas J.; Schultz, Peter G..
Department of Chemistry, The Scripps Research Institute, La Jolla,
CA, USA. Helvetica Chimica Acta (2000), 83(9), 2277-2286.
Blue-fluorescent antibodies. Simeonov, Anton;
Matsushita, Masayuki; Juban, Eric A.; Beuscher, Albert E., IV; Taylor,
Matthew J.; Wirsching, Peter; Rettig, Wolfgang; McCusker, James K.;
Stevens, Raymond C.; Millar, David P.; Schultz, Peter G.; Lerner,
Richard A.; Janda, Kim D. Department of Chemistry, The Scripps Research
Institute and the Skaggs Institute for Chemical Biology, La Jolla,
CA, USA. Science (Washington, D. C.) (2000), 290(5490), 307-313.
A Novel Copper-Mediated DNA Base Pair. Meggers,
Eric; Holland, Patrick L.; Tolman, William B.; Romesberg, Floyd E.;
Schultz, Peter G.. Department of Chemistry, The Scripps Research
Institute, La Jolla, CA, USA. Journal of the American Chemical Society
(2000), 122(43), 10714-10715.
A chemical switch for inhibitor-sensitive alleles
of any protein kinase. Bishop, Anthony C.; Ubersax, Jeffrey
A.; Petsch, Dejah T.; Matheos, Dina P.; Gray, Nathanael S.; Blethrow,
Justin; Shimizu, Eiji; Tsien, Joe Z.; Schultz, Peter G.; Rose,
Mark D.; Wood, John L.; Morgan, David O.; Shokat, Kevan M. Department
of Chemistry, Princeton University, Princeton, NJ, USA. Nature
(London) (2000), 407(6802), 395-401.
Stable and selective hybridization of oligonucleotides
with unnatural hydrophobic bases. Berger, Markus; Ogawa, Anthony
K.; McMinn, Dustin L.; Wu, Yiqin; Schultz, Peter G.; Romesberg,
Floyd E. Department of Chemistry, The Scripps Research Institute,
La Jolla, CA, USA. Angewandte Chemie, International Edition (2000),
39(16), 2940-2942.
Rational Design of an Unnatural Base Pair with
Increased Kinetic Selectivity. Ogawa, Anthony K.; Wu, Yiqin;
Berger, Markus; Schultz, Peter G.; Romesberg, Floyd E. Department
of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Journal of the American Chemical Society (2000), 122(36), 8803-8804.
Universal bases for hybridization, replication and
chain termination. Berger, Markus; Wu, Yiqin; Ogawa, Anthony
K.; McMinn, Dustin L.; Schultz, Peter G.; Romesberg, Floyd E. Department
of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Nucleic Acids Research (2000), 28(15), 2911-2914.
Efforts toward Expansion of the Genetic Alphabet:
Optimization of Interbase Hydrophobic Interactions. Wu, Yiqin;
Ogawa, Anthony K.; Berger, Markus; McMinn, Dustin L.; Schultz,
Peter G.; Romesberg, Floyd E. Department of Chemistry, The Scripps
Research Institute, La Jolla, CA, USA. Journal of the American
Chemical Society (2000), 122(32), 7621-7632.
Intracellular targets of cyclin-dependent kinase
inhibitors: identification by affinity chromatography using immobilised
inhibitors. Knockaert, M.; Gray, N.; Damiens, E.; Chang, Y-T.;
Grellier, P.; Grant, K.; Fergusson, D.; Mottram, J.; Soete, M.;
Dubremetz, J-F.; Le Roch, K.; Doerig, C.; Schultz, P. G.; Meijer,
L. Station Biologique de Roscoff, CNRS, Roscoff, Fr. Chemistry & Biology
(2000), 7(6), 411-422.
Designing small-molecule switches for protein-protein
interactions. Guo, Zhihong; Zhou, Demin; Schultz, Peter G..
Department of Chemistry and the Skaggs Institute for Chemical Biology,
The Scripps Research Institute, La Jolla, CA, USA. Science (Washington,
D. C.) (2000), 288(5473), 2042-2045.
Single-molecule protein folding: diffusion fluorescence
resonance energy transfer studies of the denaturation of chymotrypsin
inhibitor 2. Deniz, Ashok A.; Laurence, Ted A.; Beligere, Gangamani
S.; Dahan, Maxime; Martin, Andrew B.; Chemla, Daniel S.; Dawson,
Philip E.; Schultz, Peter G.; Weiss, Shimon. Department of Chemistry,
The Skaggs Institute for Chemical Biology, The Scripps Research
Institute, La Jolla, CA, USA. Proceedings of the National Academy
of Sciences of the United States of America (2000), 97(10), 5179-5184.
Progress toward the expansion of the genetic alphabet. Wu,
Yiqin; Ogawa, Anthony; McMinn, Dustin; Berger, Markus; Romesberg,
Floyd; Schultz, Peter. Department of Chemistry, CVN 22, Scripps Research
Institute, La Jolla, CA, USA. Book of Abstracts, 219th ACS National
Meeting, San Francisco, CA, March 26-30, 2000 (2000), BIOL-055. Publisher:
American Chemical Society, Washington, D. C.
A New Functional Suppressor tRNA/Aminoacyl-tRNA
Synthetase Pair for the in Vivo Incorporation of Unnatural Amino
Acids into Proteins. Wang, Lei; Magliery, Thomas J.; Liu, David
R.; Schultz, Peter G.. Department of Chemistry, The Scripps Research
Institute, La Jolla, CA, USA. Journal of the American Chemical
Society (2000), 122(20), 5010-5011.
Discovery of carbohydrate sulfotransferase inhibitors
from a kinase-directed library. Armstrong, Joshua I.; Portley,
Adam R.; Chang, Young-Tae; Nierengarten, David M.; Cook, Brian
N.; Bowman, Kendra G.; Bishop, Anthony; Gray, Nathanael S.; Shokat,
Kevan M.; Schultz, Peter G.; Bertozzi, Carolyn R. Department of
Chemistry, University of California, Berkeley, Berkeley, CA, USA.
Angewandte Chemie, International Edition (2000), 39(7), 1303-1306.
Mitotic misregulation and human aging. Ly, Danith
H.; Lockhart, David J.; Lerner, Richard A.; Schultz, Peter G.. Department
of Chemistry and the Skaggs Institute for Chemical Biology, The Scripps
Research Institute, La Jolla, CA, USA. Science (Washington, D. C.)
(2000), 287(5462), 2486-2492.
Myoseverin, a microtubule-binding molecule with
novel cellular effects. Rosania, Gustavo R.; Chang, Young-Tae;
Perez, Omar; Sutherlin, Daniel; Dong, Helin; Lockhart, David J.;
Schultz, Peter G.. The Scripps Research Institute, San Diego, CA,
USA. Nature Biotechnology (2000), 18(3), 304-308
Efforts toward the Expansion of the Genetic Alphabet:
Information Storage and Replication with Unnatural Hydrophobic
Base Pairs. Ogawa, Anthony K.; Wu, Yiqin; McMinn, Dustin L.;
Liu, Jianquan; Schultz, Peter G.; Romesberg, Floyd E. Department
of Chemistry, The Scripps Research Institute, La Jolla, CA, USA.
Journal of the American Chemical Society (2000), 122(14), 3274-3287.
Conformational Effects in Biological Catalysis:
An Antibody-Catalyzed Oxy-Cope Rearrangement. Mundorff, Emily
C.; Hanson, Michael A.; Varvak, Alex; Ulrich, Helle; Schultz, Peter
G.; Stevens, Raymond C. Department of Chemistry, University of
California, Berkeley, CA, USA. Biochemistry (2000), 39(4), 627-632.
Opportunities at the interface of chemistry and
biology. Martin, Andrew B.; Schultz, Peter G.. The Scripps
Research Institute, La Jolla, CA, USA. Trends in Cell Biology (1999),
9(12), M24-M28.
Opportunities at the interface of chemistry and
biology. Martin, A. B.; Schultz, P. G.. The Scripps Research
Institute, La Jolla, CA, USA. Trends in Genetics (1999), 15(12),
M24-M28
Mutational Analysis of the Affinity Maturation of
Antibody 48G7. Yang, Priscilla L.; Schultz, Peter G.. Department
of Chemistry, University of California, Berkeley, CA, USA. Journal
of Molecular Biology (1999), 294(5), 1191-1201.
Efforts toward Expansion of the Genetic Alphabet:
DNA Polymerase Recognition of a Highly Stable, Self-Pairing Hydrophobic
Base. McMinn, Dustin L.; Ogawa, Anthony K.; Wu, Yiqin; Liu,
Jianquan; Schultz, Peter G.; Romesberg, Floyd E. Department of
Chemistry, The Scripps Research Institute, La Jolla, CA, USA. Journal
of the American Chemical Society (1999), 121(49), 11585-11586.
Selective Antibody-Catalyzed Solvolysis of endo-2-Norbornyl
Mesylate. Ma, Lifu; Sweet, Elizabeth H.; Schultz, Peter G..
Department of Chemistry, The Scripps Research Institute, La Jolla,
CA, USA. Journal of the American Chemical Society (1999), 121(43),
10227-10228.
Versatile fluorescence labeling method using activated
esters on solid support. Chang, Young-Tae; Schultz, Peter G..
Department of Chemistry, Scripps Research Institute, La Jolla,
CA, USA. Bioorganic & Medicinal Chemistry Letters (1999), 9(17),
2479-2482.
Observing single biomolecule reactions. Weiss,
Shimon; Dahan, Maxime; Lacoste, Thilo; Glass, Jennifer; Laurence,
Ted; Chemla, Daniel S.; Deniz, Ashok; Ting, Alice; Grunwell, Jocelyn;
Faulhaber, Ann E.; Schultz, Peter G.. Materials Sciences and Physical
Biosciencs Divisions, Lawrence Berkeley National Laboratory, Berkeley,
CA, USA. Book of Abstracts, 218th ACS National Meeting, New Orleans,
Aug. 22-26 (1999), PHYS-080. Publisher: American Chemical Society,
Washington, D. C.
A Model for Hydride Transfer in Thymidylate Synthase
Based on Unnatural Amino Acid Mutagenesis. Barrett, J. E.;
Lucero, C. M.; Schultz, P. G.. Department of Chemistry, The Scripps
Research Institute, La Jolla, CA, USA. Journal of the American
Chemical Society (1999), 121(34), 7965-7966.
Temporal fluctuations of fluorescence resonance
energy transfer between two dyes conjugated to a single protein. Ha,
Taekjip; Ting, Alice Y.; Liang, Joy; Deniz, Ashok A.; Chemla, Daniel
S.; Schultz, Peter G.; Weiss, Shimon. Materials Sciences Division,
Lawrence Berkeley National Laboratory, Berkeley, CA, USA. Chemical
Physics (1999), 247(1), 107-118.
Ratiometric measurement and identification of single
diffusing molecules. Dahan, Maxime; Deniz, Ashok A.; Ha, Taekjip;
Chemla, Daniel S.; Schultz, Peter G.; Weiss, Shimon. Materials
Sciences Division, Lawrence Berkeley National Laboratory, Berkeley,
CA, USA. Chemical Physics (1999), 247(1), 85-106.
A mutational study of a diels-alderase catalytic
antibody. Romesberg, Floyd E.; Schultz, Peter G.. Howard Hughes
Medical Institute and the Department of Chemistry, University of
California, Berkeley, Berkeley, CA, USA. Bioorganic & Medicinal
Chemistry Letters (1999), 9(13), 1741-1744.
Cyclic and linear oligocarbamate ligands for human
thrombin. Cho, Charles Y.; Liu, Corey W.; Wemmer, David E.;
Schultz, Peter G.. Department of Chemistry, University of California,
Berkeley, CA, USA. Bioorganic & Medicinal Chemistry (1999),
7(6), 1171-1179.
DNA-based assembly of gold nanocrystals. Loweth,
Colin J.; Caldwell, W. Brett; Peng, Xiaogang; Alivisatos, A. Paul;
Schultz, Peter G.. Howard Hughes Medical Institute Department of
Chemistry, University of California at Berkeley, Berkeley, CA, USA.
Angewandte Chemie, International Edition (1999), 38(12), 1808-1812.
Synthesis and application of functionally diverse
2,6,9-trisubstituted purine libraries as CDK inhibitors. Chang,
Young-Tae; Gray, Nathanael S.; Rosania, Gustavo R.; Sutherlin,
Daniel P.; Kwon, Soojin; Norman, Thea C.; Sarohia, Radhika; Leost,
Maryse; Meijer, Laurent; Schultz, Peter G.. Lawrence Berkeley National
Laboratory and the Howard Hughes Medical Institute, Department
of Chemistry, University of California, Berkeley, CA, USA. Chemistry & Biology
(1999), 6(6), 361-375.
Single-pair fluorescence resonance energy transfer
on freely diffusing molecules: observation of Forster distance
dependence and subpopulations. Deniz, Ashok A.; Dahan, Maxime;
Grunwell, Jocelyn R.; Ha, Taekjip; Faulhaber, Ann E.; Chemla, Daniel
S.; Weiss, Shimon; Schultz, Peter G.. Howard Hughes Medical Institute,
Department of Chemistry, University of California, Berkeley, CA,
USA. Proceedings of the National Academy of Sciences of the United
States of America (1999), 96(7), 3670-3675.
Uncoupling of transfer of the presequence and unfolding
of the mature domain in precursor translocation across the mitochondrial
outer membrane. Kanamori, Takashi; Nishikawa, Shuh-ichi; Nakai,
Masato; Shin, Injae; Schultz, Peter G.; Endo, Toshiya. Department
of Chemistry, Faculty of Science, Nagoya University, Nagoya, Japan.
Proceedings of the National Academy of Sciences of the United States
of America (1999), 96(7), 3634-3639.
SDS capillary gel electrophoresis of proteins in
microfabricated channels. Yao, Shao; Anex, Deon S.; Caldwell,
W. Brett; Arnold, Don W.; Smith, Katherine B.; Schultz, Peter G..
Department of Chemistry, Scripps Research Institute, La Jolla,
CA, USA. Proceedings of the National Academy of Sciences of the
United States of America (1999), 96(10), 5372-5377.
A cyclin-dependent kinase inhibitor inducing cancer
cell differentiation: biochemical identification using Xenopus
egg extracts. Rosania, Gustavo R.; Merlie, John, Jr.; Gray,
Nathanael; Chang, Young-Tae; Schultz, Peter G.; Heald, Rebecca.
Department of Chemistry and Howard Hughes Medical Institute, University
of California, Berkeley, CA, USA. Proceedings of the National Academy
of Sciences of the United States of America (1999), 96(9), 4797-4802.
Progress toward the evolution of an organism with
an expanded genetic code. Liu, David R.; Schultz, Peter G..
Department of Chemistry, University of California, Berkeley, CA,
USA. Proceedings of the National Academy of Sciences of the United
States of America (1999), 96(9), 4780-4785.
Single-molecule fluorescence spectroscopy of enzyme
conformational dynamics and cleavage mechanism. Ha, Taekjip;
Ting, Alice Y.; Liang, Joy; Caldwell, W. Brett; Deniz, Ashok A.;
Chemla, Daniel S.; Schultz, Peter G.; Weiss, Shimon. Materials
Sciences Division, Lawrence Berkeley National Laboratory, Berkeley,
CA, USA. Proceedings of the National Academy of Sciences of the
United States of America (1999), 96(3), 893-898.
Generating new molecular function: a lesson from
nature. Liu, David R.; Schultz, Peter G.. Howard Hughes Medical
Institute and Department of Chemistry, University of California,
Berkeley, Berkeley, CA, USA. Angewandte Chemie, International Edition
(1999), 38(1/2), 37-54.
Tyrosine 146 of Thymidylate Synthase Assists Proton
Abstraction from the 5-Position of 2'-Deoxyuridine 5'-Monophosphate. Liu,
Yaoquan; Barrett, Jeannie E.; Schultz, Peter G.; Santi, Daniel
V. Departments of Biochemistry and Biophysics and Department of
Pharmaceutical Chemistry, University of California at San Francisco,
San Francisco, CA, USA. Biochemistry (1999), 38(2), 848-852.
Bringing biological solutions to chemical problems. Schultz,
Peter G.. Department of Chemistry, University of California, Berkeley,
CA, USA. Proceedings of the National Academy of Sciences of the United
States of America (1998), 95(25), 14590-14591.
A biosynthetic approach for the incorporation of
unnatural amino acids into proteins. Thorson, Jon S.; Cornish,
Virginia W.; Barrett, Jeannie E.; Cload, Sharon T.; Yano, Takato;
Schultz, Peter G.. Department of Chemistry, Howard Hughes Medical
Institute, University of California, Berkeley, CA, USA. Methods
in Molecular Biology (Totowa, New Jersey) (1998), 77(Protein Synthesis),
43-73.
Structural and kinetic evidence for strain in biological
catalysis. Romesberg, Floyd E.; Santarsiero, Bernard D.; Spiller,
Ben; Yin, Jun; Barnes, Dwight; Schultz, Peter G.; Stevens, Raymond
C. Howard Hughes Medical Institute and Department of Chemistry,
University of California, Berkeley, CA, USA. Biochemistry (1998),
37(41), 14404-14409.
A method for directed evolution and functional cloning
of enzymes. Pedersen, Henrik; Holder, Swen; Sutherlin, Daniel
P.; Schwitter, Urs; King, David S.; Schultz, Peter G.. Howard Hughes
Medical Institute, Department of Chemistry, University of California,
Berkeley, CA, USA. Proceedings of the National Academy of Sciences
of the United States of America (1998), 95(18), 10523-10528.
A catalytic antibody for hydrolysis of peptides. Yoon,
Seung Soo; Gong, B.; Schultz, Peter G.. Department of Chemistry,
Sung Kyun Kwan University, Suwon, S. Korea. Journal of the Korean
Chemical Society (1998), 42(4), 462-466.
A photochemical switch for controlling protein-protein
interactions. Pollitt, Sonia K.; Schultz, Peter G.. Howard
Hughes Med. Inst., Dep. Chem., Univ. California, Berkley, CA, USA.
Angewandte Chemie, International Edition (1998), 37(15), 2104-2107.
Synthesis and Screening of Linear and Cyclic Oligocarbamate
Libraries. Discovery of High Affinity Ligands for GPIIb/IIIa. Cho,
Charles Y.; Youngquist, R. Scott; Paikoff, Sari J.; Beresini, Maureen
H.; Hebert, Andrea R.; Berleau, Lea T.; Liu, Corey W.; Wemmer,
David E.; Keough, Thomas; Schultz, Peter G.. Department of Chemistry
and Howard Hughes Medical Institute, University of California,
Berkeley, CA, USA. Journal of the American Chemical Society (1998),
120(31), 7706-7718.
Exploiting chemical libraries, structure, and genomics
in the search for kinase inhibitors. Gray, Nathanael S.; Wodicka,
Lisa; Thunnissen, Andy-Mark W. H.; Norman, Thea C.; Kwon, Soojin;
Espinoza, F. Hernan; Morgan, David O.; Barnes, Georjana; LeClerc,
Sophie; Meijer, Laurent; Kim, Sung-Hou; Lockhart, David J.; Schultz,
Peter G.. Howard Hughes Med. Inst., Univ. California, Berkeley,
CA, USA. Science (Washington, D. C.) (1998), 281(5376), 533-538.
Structure of the Michaelis Complex of an Efficient
Antibody Acyl Transferase Determined by Transferred Nuclear Overhauser
Enhancement Spectroscopy. Driggers, Edward M.; Liu, Corey W.;
Wemmer, David E.; Schultz, Peter G.. Howard Hughes Medical Institute
and Department of Chemistry, University of California, Berkeley,
CA, USA. Journal of the American Chemical Society (1998), 120(29),
7395-7396.
Energetic Analysis of an Engineered Cation-π Interaction
in Staphylococcal Nuclease. Ting, Alice Y.; Shin, Injae; Lucero,
Claudia; Schultz, Peter G.. Howard Hughes Medical Institute Department
of Chemistry, University of California Lawrence Berkeley National
Laboratory, Berkeley, CA, USA. Journal of the American Chemical
Society (1998), 120(28), 7135-7136.
Antibody catalysis of peptidyl-prolyl cis-trans
isomerization in the folding of RNase T1. Ma, Lifu; Hsieh-Wilson,
Linda C.; Schultz, Peter G.. Howard Hughes Medical Institute, Department
of Chemistry, University of California, Berkeley, CA, USA. Proceedings
of the National Academy of Sciences of the United States of America
(1998), 95(13), 7251-7256.
Combinatorial approaches to materials science. Schultz,
Peter G.; Xiang, Xiao-Dong. Howard Hughes Medical Institute and Department
of Chemistry, University of California, Berkeley, CA, USA. Current
Opinion in Solid State & Materials Science (1998), 3(2), 153-158.
Mechanistic Studies of an Antibody-Catalyzed Elimination
Reaction. Romesberg, Floyd E.; Flanagan, Mark E.; Uno, Tetsuo;
Schultz, Peter G.. Howard Hughes Medical Institute and Department
of Chemistry, University of California, Berkeley, CA, USA. Journal
of the American Chemical Society (1998), 120(21), 5160-5167.
An antibody-catalyzed reduction of ketone. Yoon,
Seung Soo; Schultz, Peter G.. Department of Chemistry, Sung Kyun
Kwan University, Suwon, S. Korea. Journal of the Korean Chemical
Society (1998), 42(2), 232-235. Journal written in Korean.
Combinatorial synthesis and high throughput evaluation
of ferroelectric/dielectric thin-film libraries for microwave applications. Chang,
H.; Gao, C.; Takeuchi, I.; Yoo, Y.; Wang, J.; Schultz, P. G.; Xiang,
X.-D.; Sharma, R. P.; Downes, M.; Venkatesan, T. Materials Sciences
Division, Lawrence Berkeley National Laboratory, Berkeley, CA,
USA. Applied Physics Letters (1998), 72(17), 2185-2187.
A glycosidase antibody elicited against a chair-like
transition state analog by in vitro immunization. Yu, Jaehoon;
Choi, So Young; Moon, Kyung-Duk; Chung, Hyun-Ho; Youn, Hyun Joo;
Jeong, Sunjoo; Park, Hokoon; Schultz, Peter G.. Division Applied
Science, Korea Institute Science Technology, Seoul, S. Korea. Proceedings
of the National Academy of Sciences of the United States of America
(1998), 95(6), 2880-2884.
Immunological origins of binding and catalysis
in a Diels-Alderase antibody. Romesberg, Floyd E.; Spiller,
Ben; Schultz, Peter G.; Stevens, Raymond C. Howard Hughes Med.
Inst. and Dep. Chem., Univ. California, Berkeley, CA, USA. Science
(Washington, D. C.) (1998), 279(5358), 1929-1933.
Identification of a blue photoluminescent composite
material from a combinatorial library. Wang, Jingsong; Yoo,
Young; Gao, Chen; Takeuchi, Ichiro; Sun, Xiaodong; Chang, Hauyee;
Xiang, X. -D.; Schultz, Peter G.. Materials Sci. Div., Lawrence
Berkeley National Lab., Berkeley, CA, USA. Science (Washington,
D. C.) (1998), 279(5357), 1712-1714.
Mechanistic Studies of an Antibody-Catalyzed Pericyclic
Rearrangement. Driggers, Edward M.; Cho, Ho S.; Liu, Corey
W.; Katzka, Catherine P.; Braisted, Andrew C.; Ulrich, Helle D.;
Wemmer, David E.; Schultz, Peter G.. Department of Chemistry, University
of California, Berkeley, CA, USA. Journal of the American Chemical
Society (1998), 120(9), 1945-1958.
Trapping of the C5 Methylene Intermediate in Thymidylate
Synthase. Barrett, J. E.; Maltby, D. A.; Santi, D. V.; Schultz,
P. G.. Department of Chemistry, University of California at Berkeley,
Berkeley, CA, USA. Journal of the American Chemical Society (1998),
120(2), 449-450.
Analysis of the Role of the Active Site Tyrosine
in Human Glutathione Transferase A1-1 by Unnatural Amino Acid Mutagenesis. Thorson,
Jon S.; Shin, Injae; Chapman, Eli; Stenberg, Gun; Mannervik, Bengt;
Schultz, Peter G.. Department of Biochemistry, Uppsala University
Biomedical Center, Uppsala, Swed. Journal of the American Chemical
Society (1998), 120(2), 451-452.
Analysis of hapten binding and catalytic determinants
in a family of catalytic antibodies. Ulrich, Helle D.; Schultz,
Peter G.. Howard Hughes Medical Institute, Department of Chemistry,
University of California, Berkeley, Berkeley, CA, USA. Journal
of Molecular Biology (1998), 275(1), 95-111.
Alternative Modes of Substrate Distortion in Enzyme
and Antibody Catalyzed Ferrochelation Reactions. Blackwood,
Milton E., Jr.; Rush, Thomas S., III; Romesberg, Floyd; Schultz,
Peter G.; Spiro, Thomas G. Department of Chemistry, Princeton University,
Princeton, NJ, USA. Biochemistry (1998), 37(3), 779-782.
Tracing the evolution of a catalytic antibody. Moore,
Frederick L.; Ulrich, Helle D.; Schultz, Peter G.. Department of
Chemistry, University of California at Berkeley, Berkeley, CA, USA.
Proceedings - NOBCChE (1997), 24 167-171.
Analysis of Backbone Hydrogen Bonding in a β-Turn
of Staphylococcal Nuclease. Shin, Injae; Ting, Alice Y.; Schultz,
Peter G.. Howard Hughes Medical Institute, Department of Chemistry,
University of California, Lawrence Berkeley National Laboratory,
Berkeley, CA, USA. Journal of the American Chemical Society (1997),
119(51), 12667-12668.
Germline diversity within the mouse Igk-V9 gene
family. Ulrich, H. D.; Moore, Frederick L.; Schultz, Peter
G.. Department of Chemistry, Howard Hughes Medical Institute, University
of California, Berkeley, CA, USA. Immunogenetics (1997), 47(1),
91-95.
CVT-313, a specific and potent inhibitor of CDK2
that prevents neointimal proliferation. Brooks, Eric E.; Gray,
Nathanael S.; Joly, Alison; Kerwar, Suresh S.; Lum, Robert; Mackman,
Richard L.; Norman, Thea C.; Rosete, Jose; Rowe, Michael; Schow,
Steven R.; Schultz, Peter G.; Wang, Xingbo; Wick, Michael M.; Shiffman,
Dov. CV Therapeutics, Palo Alto, CA, USA. Journal of Biological
Chemistry (1997), 272(46), 29207-29211.
Synthesis of diverse ethoxyformacetal oligomers.
Toward libraries of metal-coordinating unnatural biopolymers. Hall,
Dennis G.; Schultz, Peter G.. Howard Hughes Medical Institute,
Department of Chemistry, University of California, Berkeley, CA,
USA. Tetrahedron Letters (1997), 38(45), 7825-7828.
Antibody-catalyzed glycosyl transfer reactions
from in vitro immunization. Yu, Jaehoon; Choi, So Young; Lee,
Sungsoo; Yoon, Hyun Joo; Jeong, Sunjoo; Mun, Hansuh; Park, Hokoon;
Schultz, Peter G.. Div. Appl. Sci., Korea Inst. Sci. Technol.,
Seoul, S. Korea. Chemical Communications (Cambridge) (1997), (20),
1957-1958.
Solution-phase synthesis of luminescent materials
libraries. Sun, Xiao Dong; Wang, Kai An; Yoo, Young; Wallace-Freedman,
William G.; Gao, Chen; Xiang, Xiao Dong; Schultz, Peter G.. Molecular
Design Institute, Lawrence Berkeley National Laboratory, Berkeley,
CA, USA. Advanced Materials (Weinheim, Germany) (1997), 9(13),
1046-1049.
Characterization of an 'orthogonal' suppressor tRNA
derived from E. coli tRNA2 Gln. Liu, David R.; Magliery, Thomas
J.; Schultz, Peter G.. Dep. Chem., Howard Hughes Med. Inst., Univ.
California, Berkeley, CA, USA. Chemistry & Biology (1997),
4(9), 685-691.
The combinatorial synthesis and evaluation of functional
materials. Xiang, X.-D.; Schultz, P. G.. Materials Sciences
Division, Lawrence Berkeley National Laboratory, Berkeley, CA,
USA. Physica C: Superconductivity (Amsterdam) (1997), 282-287(Pt.
1), 428-430.
Engineering a tRNA and aminoacyl-tRNA synthetase
for the site-specific incorporation of unnatural amino acids into
proteins in vivo. Liu, David R.; Magliery, Thomas J.; Pastrnak,
Miro; Schultz, Peter G.. Howard Hughes Medical Institute, Department
of Chemistry, University of California, Berkeley, CA, USA. Proceedings
of the National Academy of Sciences of the United States of America
(1997), 94(19), 10092-10097.
The interplay between binding energy and catalysis
in the evolution of a catalytic antibody. Ulrich, Helle D.;
Mundorff, Emily; Santarsiero, Bernard D.; Driggers, Edward M.;
Stevens, Raymond C.; Schultz, Peter G.. Howard Hughes Medical Institute,
Materials Science Division, Lawrence Berkeley National Laboratory
Department Chemistry, University California, Berkeley, CA, USA.
Nature (London) (1997), 389(6648), 271-275.
An Experimental Approach to Evaluating the Role
of Backbone Interactions in Proteins Using Unnatural Amino Acid
Mutagenesis. Koh, J. T.; Cornish, V. W.; Schultz, P. G.. Department
of Chemistry Howard Hughes Medical Institute, University of California,
Berkeley, CA, USA. Biochemistry (1997), 36(38), 11314-11322.
Noncoded Amino Acid Replacement Probes of the Aspartate
Aminotransferase Mechanism. Park, Youngwhan; Luo, Jikun; Schultz,
Peter G.; Kirsch, Jack F. Howard Hughes Medical Institute Department
of Chemistry, University of California, Berkeley, CA, USA. Biochemistry
(1997), 36(34), 10517-10525.
Mutational Analysis of Backbone Hydrogen Bonds in
Staphylococcal Nuclease. Chapman, Eli; Thorson, Jon S.; Schultz,
Peter G.. Howard Hughes Medical Institute Department of Chemistry,
University of California, Berkeley, CA, USA. Journal of the American
Chemical Society (1997), 119(30), 7151-7152.
Nondestructive imaging of dielectric-constant profiles
and ferroelectric domains with a scanning-tip microwave near-field
microscope. Lu, Yalin; Wei, Tao; Duewer, Fred; Lu, Yanqing;
Ming, Nai-Ben; Schultz, P. G.; Xiang, X.-D. Mol. Design Inst.,
Lawrence Berkeley Natl. Lab., Berkeley, CA, USA. Science (Washington,
D. C.) (1997), 276(5321), 2004-2006.
Structural insights into the evolution of an antibody
combining site. Wedemayer, Gary J.; Patten, Phillip A.; Wang,
Leo H.; Schultz, Peter G.; Stevens, Raymond C. Dep. Chem., Univ.
California, Berkeley, CA, USA. Science (Washington, D. C.) (1997),
276(5319), 1665-1669.
Crystal structures of the free and liganded form
of an esterolytic catalytic antibody. Wedemayer, Gary J.; Wang,
Leo H.; Patten, Phillip A.; Schultz, Peter G.; Stevens, Raymond
C. Howard Hughes Med. Inst., Dep. of Chem., Univ. of California,
Berkeley, CA, USA. Journal of Molecular Biology (1997), 268(2),
390-400.
Lessons from the immune system: From catalysis to
materials. Schultz, P. G.. Department Chemistry, University
California, Berkeley, CA, USA. Book of Abstracts, 213th ACS National
Meeting, San Francisco, April 13-17 (1997), INOR-366. Publisher:
American Chemical Society, Washington, D. C.
Combinatorial synthesis of 2,9-substituted purines. Gray,
Nathanael S.; Kwon, Soojin; Schultz, Peter G.. Howard Hughes Medical
Institute, Department of Chemistry, University of California, Berkeley,
CA, USA. Tetrahedron Letters (1997), 38(7), 1161-1164.
Synthesis and isolation of a homodimer of cadmium
selenide nanocrystals. Peng, Xiaogang; Wilson, Troy E.; Alivisatos,
A. Paul; Schultz, Peter G.. Department Chemistry, University California
Berkeley, Berkeley, CA, USA. Angewandte Chemie, International Edition
in English (1997), 36(1/2), 145-147.
Overexpression, purification, and characterization
of the catalase-peroxidase KatG from Mycobacterium tuberculosis. Johnsson,
Kai; Froland, Wayne A.; Schultz, Peter G.. Howard Hughes Medical
Institute, University California, Berkeley, CA, USA. Journal of
Biological Chemistry (1997), 272(5), 2834-2840.
Probing the environment along the protein import
pathways in yeast mitochondria by site-specific photocrosslinking. Kanamori,
Takashi; Nishikawa, Shuh-Ichi; Shin, Injae; Schultz, Peter G.;
Endo, Toshiya. Faculty Science, Nagoya University, Nagoya, Japan.
Proceedings of the National Academy of Sciences of the United States
of America (1997), 94(2), 485-490.
Development of improved tRNAs for in vitro biosynthesis
of proteins containing unnatural amino acids. Cload, Sharon
T.; Liu, David R.; Froland, Wayne A.; Schultz, Peter G.. Howard
Hughes Med. Inst., Univ. California, Berkeley, CA, USA. Chemistry & Biology
(1996), 3(12), 1033-1038.
Catalytic antibodies. Driggers, Edward M.; Schultz,
Peter G.. Howard Hughes Medical Institute, University of California,
Berkeley, CA, USA. Advances in Protein Chemistry (1996), 49(Antigen
Binding Molecules: Antibodies and T-Cell Receptors), 261-287.
Structural studies of catalytic antibodies. Stevens,
Raymond C.; Hsieh-Wilson, Linda C.; Santarsiero, Bernard D.; Wedemayer,
Gary J.; Spiller, Ben; Wang, Leo H.; Barnes, Dwight; Ulrich, Helle
D.; Patten, Phillip A.; Romesberg, Floyd E.; Schultz, Peter G.. Dep.
Chem. Howard Hughes Med. Inst., Univ. California, Berkeley, CA, USA.
Israel Journal of Chemistry (1996), 36(2), 121-132.
An Antibody-Catalyzed [2,3]-Elimination Reaction. Yoon,
Seung Soo; Oei, Yoko; Sweet, Elizabeth; Schultz, Peter G.. Department
of Chemistry, University of California, Berkeley, CA, USA. Journal
of the American Chemical Society (1996), 118(46), 11686-11687.
Building blocks for peptide and carbamate libraries. Bi,
Yingzhi; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Bioorganic & Medicinal Chemistry Letters (1996), 6(19),
2299-2300.
RNA catalysis and transition state stabilization. Prudent,
J. R.; Schultz, P. G.. Howard Hughes Medical Institute, University
California, Berkeley, CA, USA. Nucleic Acids and Molecular Biology
(1996), 10(Catalytic RNA), 383-395.
Organization of 'nanocrystal molecules' using DNA. Alivisatos,
A. Paul; Johnsson, Kai P.; Peng, Xiaogang; Wilson, Troy E.; Loweth,
Colin J.; Bruchez, Marcel P., Jr.; Schultz, Peter G.. Dep. Chem.,
Univ. California Berkeley, Berkeley, CA, USA. Nature (London) (1996),
382(6592), 609-611.
The solid phase synthesis of N-alkylcarbamate oligomers. Paikoff,
Sari J.; Wilson, Troy E.; Cho, Charles Y.; Schultz, Peter G.. Howard
Hughes Med. Inst., Univ. California, Berkeley, CA, USA. Tetrahedron
Letters (1996), 37(32), 5653-5656.
Site-Specific Protein Modification Using a Ketone
Handle. Cornish, Virginia W.; Hahn, Klaus M.; Schultz, Peter
G.. Department of Chemistry, University of California, Berkeley,
CA, USA. Journal of the American Chemical Society (1996), 118(34),
8150-8151.
Synthesis of a cyclic urea as a nonnatural biopolymer
scaffold. Kim, Jong-Man; Wilson, Troy E.; Norman, Thea C.;
Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley, CA,
USA. Tetrahedron Letters (1996), 37(30), 5309-5312.
The solid phase synthesis of oligoureas. Kim,
Jong-Man; Bi, Yingzhi; Paikoff, Sari J.; Schultz, Peter G.. Dep.
Chem., Univ. California, Berkeley, CA, USA. Tetrahedron Letters (1996),
37(30), 5305-5308.
A Structure-Based Library Approach to Kinase Inhibitors. Norman,
Thea C.; Gray, Nathanael S.; Koh, John T.; Schultz, Peter G.. Department
of Chemistry, University of California, Berkeley, CA, USA. Journal
of the American Chemical Society (1996), 118(31), 7430-7431.
Porphyrin Metalation Catalyzed by a Small RNA Molecule. Conn,
M. Morgan; Prudent, James R.; Schultz, Peter G.. Howard Hughes Medical
Institute, University of California, Berkeley, CA, USA. Journal of
the American Chemical Society (1996), 118(29), 7012-7013.
Scanning tip microwave near-field microscope. Wei,
T.; Xiang, X.-D.; Wallace-Freedman, W. G.; Schultz, P. G.. Mol. Design
Inst., Lawrence Berkeley Natl. Lab., Berkeley, CA, USA. Applied Physics
Letters (1996), 68(24), 3506-3508.
Antibody-Catalyzed Retro-Aldol Reaction. Flanagan,
Mark E.; Jacobsen, John R.; Sweet, Elizabeth; Schultz, Peter G..
Howard Hughes Medical Institute, University of California, Berkeley,
CA, USA. Journal of the American Chemical Society (1996), 118(25),
6078-6079.
Insights into antibody catalysis: structure of an
oxygenation catalyst at 1.9-.ANG. resolution. Hsieh-Wilson,
Linda C.; Schultz, Peter G.; Stevens, Raymond C. Howard Hughes
Med. Inst., Univ. California, Berkeley, CA, USA. Proceedings of
the National Academy of Sciences of the United States of America
(1996), 93(11), 5363-5367.
Antibodies with Thiol-S-Transferase Activity. Fan,
Erkang; Oei, Yoko; Sweet, Elizabeth; Uno, Tetsuo; Schultz, Peter
G.. Department of Chemistry, University of California, Berkeley,
CA, USA. Journal of the American Chemical Society (1996), 118(23),
5474-5475.
Antibody catalysis of pericyclic reactions. Ulrich,
Helle D.; Driggers, Edward M. G.; Schultz, Peter G.. Dep. Chem.,
Univ. California, Berkeley, CA, USA. Acta Chemica Scandinavica (1996),
50(4), 328-332.
In vivo selection of basic region-leucine zipper
proteins with altered DNA-binding specificities. Sera, Takashi;
Schultz, Peter G.. Howard Hughes Medical Institute, University
California, Berkeley, CA, USA. Proceedings of the National Academy
of Sciences of the United States of America (1996), 93(7), 2920-5.
An Antibody-Catalyzed Isomerization Reaction. Uno,
Tetsuo; Ku, Jung; Prudent, James R.; Huang, Anita; Schultz, Peter
G.. Howard Hughes Medical Institute, Berkeley, CA, USA. Journal of
the American Chemical Society (1996), 118(16), 3811-17.
The immunological evolution of catalysis. Patten,
Phillip A.; Gray, Nathanael S.; Yang, Priscilla L.; Marks, Cara B.;
Wedemayer, Gary J.; Boniface, J. Jay; Stevens, Raymond C.; Schultz,
Peter G.. Howard Hughes Med. Inst., Univ. California, Berkeley, CA,
USA. Science (Washington, D. C.) (1996), 271(5252), 1086-91.
Lessons from the Immune System: From Catalysis to
Materials Science. Hsieh-Wilson, Linda C.; Xiang, Xiao-Dong;
Schultz, Peter G.. Department of Chemistry, University of California,
Berkeley, CA, USA. Accounts of Chemical Research (1996), 29(3),
164-70.
Mutagenesis study of active site residues in chorismate
mutase from Bacillus subtilis. Cload, Sharon T.; Liu, David
R.; Pastor, Richard M.; Schultz, Peter G.. Department of Chemistry,
University of California, Berkeley, CA, USA. Journal of the American
Chemical Society (1996), 118(7), 1787-8.
Analysis
of active site residues in Escherichia coli chorismate mutase
by site-directed mutagenesis. Liu, David R.; Cload, Sharon
T.; Pastor, Richard M.; Schultz, Peter G.. Department of Chemistry,
University of California, Berkeley, CA, USA. Journal of the American
Chemical Society (1996), 118(7), 1789-90.
Expression
studies of catalytic antibodies. Ulrich, H. D.; Patten, P.
A.; Yang, P. L.; Romesberg, F. E.; Schultz, P. G.. Howard Hughes
Medical Institute, Department of Chemistry, University of California,
Berkeley 94720, USA Proceedings of the National Academy of Sciences
of the United States of America. (1995), 92(25), 11907-11.
The scope of
antibody catalysis. Jacobsen, John R.; Schultz, Peter G.. University
of California at Berkeley, Berkeley, CA, USA. Current Opinion in
Structural Biology (1995), 5(6), 818-24.
A class of
cobalt oxide magnetoresistance materials discovered with combinatorial
synthesis. Briceno, Gabriel; Chang, Hauyee; Sun, Xiaodong;
Schultz, Peter G.; Xiang, X.-D. Molecular Design Inst., Lawrence
Berkeley Lab., Berkeley, CA, USA. Science (Washington, D. C.) (1995),
270(5234), 273-5.
From molecular
diversity to catalysis: lessons from the immune system. Schultz,
Peter G.; Lerner, Richard A. Howard Hughes Med. Inst., Univ. California,
Berkeley, CA, USA. Science (Washington, D. C.) (1995), 269(5232),
1835-42.
Probing the
structural determinants of a catalytic RNA with isomerase activity. Prudent,
James R.; Staunton, Joanna; Schultz, Peter G.. Department of Chemistry,
University of California, Berkeley, CA, USA. Journal of the American
Chemical Society (1995), 117(40), 10145-6.
Analysis of
Hydrogen Bonding Strengths in Proteins Using Unnatural Amino Acids. Thorson,
Jon S.; Chapman, Eli; Schultz, Peter G.. Department of Chemistry,
University of California, Berkeley, CA, USA. Journal of the American
Chemical Society (1995), 117(36), 9361-2.
Photochemically
initiated protein splicing. Cook, Sandra N.; Jack, William
E.; Xiong, Xiaofeng; Danley, Lora E.; Ellman, Jonathan A.; Schultz,
Peter G.; Noren, Christopher J. New England Biolabs, Beverly, MA,
USA. Angewandte Chemie, International Edition in English (1995),
34(15), 1629-30.
Alternate protein
frameworks for molecular recognition. Ku, Jung; Schultz, Peter
G.. Howard Hughes Med. Inst., Univ. California, Berkeley, CA, USA.
Proceedings of the National Academy of Sciences of the United States
of America (1995), 92(14), 6552-6.
A combinatorial
approach to materials discovery. Xiang, X.-D.; Sun, Xiaodong;
Briceno, Gabriel; Lou, Yulin; Wang, Kai-An; Chang, Hauyee; Wallace-Freedman,
William G.; Chen, Sung-Wei; Schultz, Peter G.. Molecular Design
Inst., Lawrence Berkeley Lab., Berkeley, CA, USA. Science (Washington,
D. C.) (1995), 268(5218), 1738-40.
Site-directed
mutagenesis with an expanded genetic code. Mendel, David; Cornish,
Virginia W.; Schultz, Peter G.. Lilly Res. Lab., Eli Lilly and
Co., Indianapolis, IN, USA. Annual Review of Biophysics and Biomolecular
Structure (1995), 24 435-62.
Mechanistic
Studies of Antibody-Catalyzed Pyrimidine Dimer Photocleavage. Jacobsen,
John R.; Cochran, Andrea G.; Stephans, James C.; King, David S.;
Schultz, Peter G.. Department of Chemistry, University of California,
Berkeley, CA, USA. Journal of the American Chemical Society (1995),
117(20), 5453-61.
Studies on
the Mechanism of Action of Isoniazid and Ethionamide in the Chemotherapy
of Tuberculosis. Johnsson, Kai; King, David S.; Schultz, Peter
G.. Department of Chemistry, University of California, Berkeley,
CA, USA. Journal of the American Chemical Society (1995), 117(17),
5009-10.
Probing protein
structure and function with an expanded genetic code. Cornish,
Virginia W.; Mendel, David; Schultz, Peter G.. Dep. Chem., Univ.
California, Berkeley, CA, USA. Angewandte Chemie, International
Edition in English (1995), 34(6), 621-33.
Nicotinic receptor-binding
site probed with unnatural amino-acid-incorporation in intact-cells. Nowack,
M.W.; Kearney, P.C.; Sampson, J.R.; Saks, M.E.; Labarca, C. G.;
Silverman, S.K.; Zhong, W.; Thorson, J.; Abelson, J.N.; Davidson,
J.N.; Schultz, P.G.; Dougherty, D.A.; Lester, H.A.. Science (Washington,
D.C., 1883-) (1995), 268 (5209): 439-442.
A strategy
for the chemical synthesis of nanostructures. Mueller, Wolfgang
T.; Klein, David L.; Lee, Thomas; Clarke, John; McEuen, Paul L.;
Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley, CA,
USA. Science (Washington, D. C.) (1995), 268(5208), 272-3.
Novel biopolymers
for drug discovery. Moran, Edmund J.; Wilson, Troy E.; Cho,
Charles Y.; Cherry, Sara R.; Schultz, Peter G.. Dep. Chem., Univ.
California, Berkeley, CA, USA. Biopolymers (1995), 37(3), 213-19.
Linear Free
Energy Analysis of Hydrogen Bonding in Proteins. Thorson, Jon
S.; Chapman, Eli; Murphy, Elizabeth C.; Schultz, Peter G.; Judice,
J. Kevin. Howard Hughes Medical Institute, University of California,
Berkeley, CA, USA. Journal of the American Chemical Society (1995),
117(3), 1157-8.
Phage display
of catalytically active staphylococcal nuclease. Ku, Jung;
Schultz, Peter G.. Department Chemistry, University of California,
Berkeley, CA, USA. Bioorganic & Medicinal Chemistry (1994),
2(12), 1413-15.
DNA quadruplexes:
from telomeres to aptamers. Feigon, Juli; Smith, Flint W.;
Macaya, Roman F.; Schultz, Peter. Biochemistry and Molecular Biology
Institute, University California, Los Angeles, CA, USA. Editor(s):
Sarma, Ramswamy H.; Sarma, Mukti H. Struct. Biol. State of the
Art, Proc. Conversation Discip. Biomol. Stereodyn., 8th (1994),
Meeting Date 1993, 2 127-34, 4 plates. Publisher: Adenine, Schenectady,
N. Y.
Stabilizing
and Destabilizing Effects of Placing ;β-Branched Amino
Acids in Protein α-Helixes. Cornish, Virginia W.; Kaplan,
Mark I.; Veenstra, David L.; Kollman, Peter A.; Schultz, Peter
G.. Department of Chemistry, University of California, Berkeley,
CA, USA. Biochemistry (1994), 33(40), 12022-31.
Expanding the
scope of RNA catalysis. Prudent, James R.; Uno, Tetsuo; Schultz,
Peter G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Science
(Washington, DC, United States) (1994), 264(5167), 1924-7.
Catalysis of
carbamate hydrolysis by an antibody. Van Vranken, David L.;
Panomitros, Demetra; Schultz, Peter G.. Dep. Chem., Univ. California,
Berkeley, CA, USA. Tetrahedron Letters (1994), 35(23), 3873-6.
Antibody catalysis
of peptide bond formation. Jacobsen, John R.; Schultz, Peter
G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Proceedings
of the National Academy of Sciences of the United States of America
(1994), 91(13), 5888-92.
A new tool
for studying protein structure and function. Cornish, Virginia
W.; Schultz, Peter G.. Univ. California, Berkeley, CA, USA. Current
Opinion in Structural Biology (1994), 4(4), 601-7.
Mechanistic
Studies of the Oxidation of Isoniazid by the Catalase Peroxidase
from Mycobacterium tuberculosis. Johnsson, Kai; Schultz, Peter
G.. Department of Chemistry, University of California, Berkeley,
CA, USA. Journal of the American Chemical Society (1994), 116(16),
7425-6.
Mechanistic
Studies of an Antibody-Catalyzed Elimination Reaction. Shokat,
Kevan; Uno, Tetsuo; Schultz, Peter G.. Department of Chemistry,
University of California, Berkeley, CA, USA. Journal of the American
Chemical Society (1994), 116(6), 2261-70.
A permutational
approach toward protein-DNA recognition. Huang, Lixuan; Sera,
Takashi; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Proceedings of the National Academy of Sciences of the
United States of America (1994), 91(9), 3969-73.
Site-specific
incorporation of biophysical probes into proteins. Cornish,
Virginia W.; Benson, David R.; Altenbach, Christian A.; Hideg,
Kalman; Hubbell, Wayne L.; Schultz, Peter G.. Dep. Chem., Univ.
California, Berkeley, CA, USA. Proceedings of the National Academy
of Sciences of the United States of America (1994), 91(8), 2910-14.
On the path
to antibody glycosidases. Yu, Jaehoon; Hsieh, Linda C.; Kochersperger,
Lynn; Yonkovich, Shirlee; Stephans, James C.; Gallop, Mark A.;
Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley, CA,
USA. Angewandte Chemie (1994), 106(3), 327-9 (See also Angew. Chem.,
Int. Ed. Engl., 1994, 33(3), 339-41). Journal written in German.
An Antibody-Catalyzed
Oxy-Cope Rearrangement. Braisted, Andrew C.; Schultz, Peter
G.. Department of Chemistry, University of California, Berkeley,
CA, USA. Journal of the American Chemical Society (1994), 116(5),
2211-12.
Antibody-Catalyzed
Prodrug Activation. Campbell, David A.; Gong, Bing; Kochersperger,
Lynn M.; Yonkovich, Shirlee; Gallop, Mark A.; Schultz, Peter G..
Affymax Research Institute, Palo Alto, CA, USA. Journal of the
American Chemical Society (1994), 116(5), 2165-6.
Stereoselective
Antibody-Catalyzed Oxime Formation. Uno, Tetsuo; Gong, Bing;
Schultz, Peter G.. Department of Chemistry, University of California,
Berkeley, CA, USA. Journal of the American Chemical Society (1994),
116(3), 1145-6.
An Efficient
Antibody-Catalyzed Oxygenation Reaction. Hsieh, Linda C.; Stephans,
James C.; Schultz, Peter G.. Department of Chemistry, University
of California, Berkeley, CA, USA. Journal of the American Chemical
Society (1994), 116(5), 2167-8.
Artificial
nucleases. Pei, Dehua; Schultz, Peter G.. Dep. Chem., Univ.
Calif., Berkeley, CA, USA. Cold Spring Harbor Monograph Series
(1993), 25(NUCLEASES (2ND ED.)), 317-40.
Probing the
role of loop 2 in Ras function with unnatural amino acids. Chung,
Hyun Ho; Benson, David R.; Cornish, Virginia W.; Schultz, Peter
G.. Lawrence Berkeley Lab., Univ. California, Berkeley, CA, USA.
Proceedings of the National Academy of Sciences of the United States
of America (1993), 90(21), 10145-9.
An unnatural
biopolymer. Cho, Charles Y.; Moran, Edmund J.; Cherry, Sara
R.; Stephans, James C.; Fodor, Stephen P. A.; Adams, Cynthia L.;
Sundaram, Arathi; Jacobs, Jeffrey W.; Schultz, Peter G.. Dep. Chem.,
Univ. California, Berkeley, CA, USA. Science (Washington, DC, United
States) (1993), 261(5126), 1303-5.
Isoabzymes:
Structurally and mechanistically similar catalytic antibodies from
the same immunization. Angeles, Thelma S.; Smith, Rodger G.;
Darsley, Michael J.; Sugasawara, Renee; Sanchez, Rosa I.; Kenten,
John; Schultz, Peter G.; Martin, Mark T. IGEN, Inc., Rockville,
MD, USA. Biochemistry (1993), 32(45), 12128-35.
Probing the
mechanism of staphylococcal nuclease with unnatural amino acids:
kinetic and structural studies. Judice, J. Kevin; Gamble, Theresa
R.; Murphy, Elizabeth C.; de Vos, Abraham M.; Schultz, Peter G..
Dep. Chem., Univ. California, Berkeley, CA, USA. Science (Washington,
DC, United States) (1993), 261(5128), 1578-81.
Antibody catalysis
of difficult chemical transformations. Schultz, Peter G.; Lerner,
Richard A. Dep. Chem., Univ. California, Berkeley, CA, USA. Accounts
of Chemical Research (1993), 26(8), 391-5.
Controlling
chemical reactivity with antibodies. Hsieh, Linda C.; Yonkovich,
Shirlee; Kochersperger, Lynn; Schultz, Peter G.. Dep. Chem., Univ.
California, Berkeley, CA, USA. Science (Washington, DC, United
States) (1993), 260(5106), 337-9.
Probing a catalytic
antibody active site using spin-labeled haptens. Skerker, Paul
S.; Jacobs, Jeffrey W.; Clark, Douglas S.; Schultz, Peter G.. Dep.
Chem. Eng., Univ. California, Berkeley, CA, USA. Bioorganic & Medicinal
Chemistry Letters (1993), 3(2), 285-8.
Probing the
role of lysine 16 in ras p21 protein with unnatural amino acids. Chung,
Hyun Ho; Benson, David R.; Schultz, Peter G.. Dep. Chem., Univ.
California, Berkeley, CA, USA. Journal of the American Chemical
Society (1993), 115(14), 6414-15.
Protein biosynthesis
with conformationally restricted amino acids. Mendel, David;
Ellman, Jonathan; Schultz, Peter G.. Dep. Chem., Univ. California,
Berkeley, CA, USA. Journal of the American Chemical Society (1993),
115(10), 4359-60.
Increasing
the chemical potential of the germ-line antibody repertoire. Sarvetnick,
Nora; Gurushanthaiah, Deepak; Han, Nianhe; Prudent, James; Schultz,
Peter; Lerner, Richard. Dep. Neutropharmacol., Scripps Res. Inst.,
La Jolla, CA, USA. Proceedings of the National Academy of Sciences
of the United States of America (1993), 90(9), 4008-11.
A genetic approach
to the generation of antibodies with enhanced catalytic activities. Lesley,
Scott A.; Patten, Phillip A.; Schultz, Peter G.. Dep. Chem., Univ.
California, Berkeley, CA, USA. Proceedings of the National Academy
of Sciences of the United States of America (1993), 90(4), 1160-5.
Probing the
structure and mechanism of Ras protein with an expanded genetic
code. Chung, Hyun Ho; Benson, David R.; Schultz, Peter G..
Dep. Chem., Univ. California, Berkeley, CA, USA. Science (Washington,
DC, United States) (1993), 259(5096), 806-9.
Recent advances
in catalytic antibodies. Scanlan, Thomas; Schultz, Peter G..
Dep. Chem., Univ. California, Berkeley, CA, USA. Advances in Detailed
Reaction Mechanisms (1992), 2(Mech. Biol. Importance), 1-22.
Progress toward
the generation of antibodies containing catalytic dyads. Jackson,
David Y.; Schultz, Peter G.. Department Chemistry, University California,
Berkeley, CA, USA. Editor(s): Yoshida, Zen-ichi; Ohshiro, Yoshiki.
New Aspects Org. Chem. II, Proc. Int. Kyoto Conf., 5th (1992),
Meeting Date 1991, 469-75. Publisher: Kodansha, Tokyo, Japan.
Peptide ligands
for a sugar-binding protein isolated from a random peptide library. Oldenburg,
Kevin R.; Loganathan, Duraikkannu; Goldstein, Irwin J.; Schultz,
Peter G.; Gallop, Mark A. Dep. Bioorg. Chem., Affymax Res. Inst.,
Palo Alto, CA, USA. Proceedings of the National Academy of Sciences
of the United States of America (1992), 89(12), 5393-7.
An efficient
antibody-catalyzed aminoacylation reaction. Jacobsen, John
R.; Prudent, James R.; Kochersperger, Lynn; Yonkovich, Shirlee;
Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley, CA,
USA. Science (Washington, DC, United States) (1992), 256(5055),
365-7.
Probing protein
stability with unnatural amino acids. Mendel, David; Ellman,
Jonathan A.; Chang, Zhiyuh; Veenstra, David L.; Kollman, Peter
A.; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Science (Washington, DC, United States) (1992), 256(5065),
1798-802.
An antibody-catalyzed
dehydration reaction. Uno, Tetsuo; Schultz, Peter G.. Dep.
Chem., Univ. California, Berkeley, CA, USA. Journal of the American
Chemical Society (1992), 114(16), 6573-4.
Photolithographic
immobilization of biopolymers on solid supports. Rozsnyai,
Lawrence F.; Fodor, Stephen P. A.; Schultz, Peter G.; Benson, D.
R. Dep. Chem., Univ. California, Berkeley, CA, USA. Angewandte
Chemie, International Edition (1992), 31(6), 759-61.
Activation
parameters and stereochemistry of antibody-catalyzed Claisen rearrangement. Jackson,
David Y.; Liang, Michael N.; Bartlett, Paul A.; Schultz, Peter
G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Angewandte
Chemie, International Edition (1992), 31(2), 182-3).
Site-specific
incorporation of novel backbone structures into proteins. Ellman,
Jonathan A.; Mendel, David; Schultz, Peter G.. Dep. Chem., Univ.
California, Berkeley, CA, USA. Science (Washington, DC, United
States) (1992), 255(5041), 197-200.
A chromogenic
assay for screening large antibody libraries. Gong, Bing; Lesley,
Scott A.; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Journal of the American Chemical Society (1992), 114(4),
1486-7.
Stereospecific
antibody-catalyzed reduction of an α-keto amide. Nakayama,
Grace R.; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Journal of the American Chemical Society (1992), 114(2),
780-1.
Chemistry at
the Frontiers of Medicine, October 28-29, 1991, Houston, Texas. [In:
Proc. Robert A. Welch Found. Conf. Chem. Res., 1991; 35]. Samuelsson,
Bengt; Schultz, Peter G.; Bartlett, Paul A.; Wlodawer, Alexander;
Schreiber, Stuart L.; Krebs, Edwin G.; Ohno, Masaji; Boger, Dale
L.; Stadtman, Earl R.; et al. USA. (1991), 256 pp. Publisher: (Robert
A. Welch Foundation, Houston, Texas).
The generation
of antibody combining sites containing catalytic residues. Shokat,
Kevan M.; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Ciba Foundation Symposium (1991), 159(Catal. Antibodies),
118-34.
Characterization
of the mechanism of action of a catalytic antibody. Martin,
Mark T.; Schantz, Allen R.; Schultz, Peter G.; Rees, Anthony R.
IGEN Inc., Rockville, MD, USA. Ciba Foundation Symposium (1991),
159(Catal. Antibodies), 188-200.
Catalytic antibodies:
an overview of design strategies and their applications. Schultz,
Peter G.; Shokat, Kevan M. Dep. Chem., Univ. California, Berkeley,
CA, USA. Proceedings of the Robert A. Welch Foundation Conference
on Chemical Research (1991), 35(Chem. Front. Med.), 19-42.
Approaches
to the design of semisynthetic metal-dependent catalytic antibodies. Nakayama,
Grace R.; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Ciba Foundation Symposium (1991), 159(Catal. Antibodies),
72-90.
Catalytic antibodies. Shokat,
Kevan M.; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Methods in Enzymology (1991), 203(Mol. Des. Model.: Concepts
Appl., Pt. B.), 327-51.
Biosynthetic
method for introducing unnatural amino acids site-specifically
into proteins. Ellman, Jon; Mendel, David; Anthony-Cahill,
Spencer; Noren, Christopher J.; Schultz, Peter G.. Dep. Chem.,
Univ. California, Berkeley, CA, USA. Methods in Enzymology (1991),
202(Mol. Des. Model.: Concepts Appl., Pt. A), 301-36.
A combinatorial
approach toward DNA recognition. Pei, Dehua; Ulrich, Helle
D.; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Science (Washington, DC, United States) (1991), 253(5026),
1408-11.
Antibody-catalyzed
hydrolysis of phosphate monoesters. Scanlan, Thomas S.; Prudent,
James R.; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Journal of the American Chemical Society (1991), 113(24),
9397-8.
Hybrid enzymes
and the sequence-specific cleavage of nucleic acids. Corey,
David R.; Zuckermann, Ronald N.; Schultz, Peter G.. Univ. California,
Berkeley, CA, USA. Bioorganic Chemistry Frontiers (1991), 2 1-31.
Recent advances
in catalytic antibodies. Scanlon, Thomas S.; Schultz, Peter
G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Philosophical
Transactions of the Royal Society of London, Series B: Biological
Sciences (1991), 332(1263), 157-64.
General approach
to the synthesis of short α-helical peptides. Jackson,
David Y.; King, David S.; Chmielewski, Jean; Singh, Sunil; Schultz,
Peter G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Journal
of the American Chemical Society (1991), 113(24), 9391-2.
Engineering
protein specificity: gene manipulation with semisynthetic nucleases. Pei,
Dehua; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Journal of the American Chemical Society (1991), 113(24),
9398-400.
Mechanistic
studies of a tyrosine-dependent catalytic antibody. Martin,
Mark T.; Napper, Andrew D.; Schultz, Peter G.; Rees, Anthony R.
IGEN, Inc., Rockville, MD, USA. Biochemistry (1991), 30(40), 9757-61.
At the crossroads
of chemistry and immunology: catalytic antibodies. Lerner,
Richard A.; Benkovic, Stephen J.; Schultz, Peter G.. Dep. Chem.,
Scripps Res. Inst., La Jolla, CA, USA. Science (Washington, DC,
United States) (1991), 252(5006), 659-67.
Antibody-catalyzed
bimolecular imine formation. Cochran, Andrea G.; Pham, Tony;
Sugasawara, Renee; Schultz, Peter G.. Dep. Chem., Univ. California,
Berkeley, CA, USA. Journal of the American Chemical Society (1991),
113(17), 6670-2.
Monoclonal
antibodies with sequence specific affinity for a stem-loop structure
in DNA. Chmielewski, Jean; Schultz, Peter. Dep. Chem., Univ.
California, Berkeley, CA, USA. Tetrahedron (1991), 47(14-15), 2563-72.
An antibody-catalyzed
cis-trans isomerization reaction. Jackson, David Y.; Schultz,
Peter G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Journal
of the American Chemical Society (1991), 113(6), 2319-21.
A mutagenesis
study of a catalytic antibody. Jackson, David Y.; Prudent,
James R.; Baldwin, Enoch P.; Schultz, Peter G.. Dep. Chem., Univ.
California, Berkeley, CA, USA. Proceedings of the National Academy
of Sciences of the United States of America (1991), 88(1), 58-62.
Construction
of a light-activated protein by unnatural amino acid mutagenesis. Mendel,
David; Ellman, Jonathan A.; Schultz, Peter G.. Dep. Chem., Univ.
California, Berkeley, CA, USA. Journal of the American Chemical
Society (1991), 113(7), 2758-60.
A general and
efficient route for chemical aminoacylation of transfer RNAs. Robertson,
Stephanie A.; Ellman, Jonathan A.; Schultz, Peter G.. Dep. Chem.,
Univ. California, Berkeley, CA, USA. Journal of the American Chemical
Society (1991), 113(7), 2722-9.
Redirecting
the immune response: ligand-mediated immunogenicity. Shokat,
Kevan M.; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Journal of the American Chemical Society (1991), 113(5),
1861-2.
Semisynthetic
catalytic antibodies. Pollack, Scott J.; Schultz, Peter G..
Dep. Chem., Univ. California, Berkeley, CA, USA. Editor(s): Hook,
Jerry B.; Poste, George. Protein design and the Development
of New Therapeutics and Vaccines (1990), 371-94. Publisher:
Plenum, New York, N. Y.
Site-specific
cleavage of duplex DNA by a semisynthetic nuclease via triple-helix
formation. Pei, Dehua; Corey, David R.; Schultz, Peter G..
Dep. Chem., Univ. California, Berkeley, CA, USA. Proceedings of
the National Academy of Sciences of the United States of America
(1990), 87(24), 9858-62.
Catalytic antibodies:
a new class of transition-state analogs to produce hydrolytic antibodies. Shokat,
Kevan M.; Ko, Marcia K.; Scanlan, Thomas S.; Kochersperger, Lynn;
Yonkovich, Shirlee; Thaisrivongs, Suvit; Schultz, Peter G.. Dep.
Chem., Univ. California, Berkeley, CA, USA. Angewandte Chemie,
International. Edition (1990), 29(11), 1296-303).
Antibody-catalyzed
porphyrin metallation. Cochran, Andrea G.; Schultz, Peter G..
Dep. Chem., Univ. California, Berkeley, CA, USA. Science (Washington,
D. C., 1883-) (1990), 249(4970), 781-3.
Peroxidase
activity of an antibody-heme complex. Cochran, Andrea G.; Schultz,
Peter G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Journal
of the American Chemical Society (1990), 112(25), 9414-15.
An antibody-catalyzed
bimolecular Diels-Alder reaction. Braisted, Andrew C.; Schultz,
Peter G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Journal
of the American Chemical Society (1990), 112(20), 7430-1.
Catalytic antibodies. Schultz,
Peter G.; Lerner, Richard A.; Benkovic, Stephen J. Univ. California,
Berkeley, CA, USA. Chemical & Engineering News (1990), 68(22),
26-8, 30-3, 36, 38-40.
Catalytic antibodies. Shokat,
K. M.; Schultz, P. G.. Dep. Chem., Univ. California, Berkeley, CA,
USA. Annual Review of Immunology (1990), 8 335-63.
Site-specific
cleavage of duplex DNA with a λ repressor-staphylococcal nuclease
hybrid. Pei, Dehua; Schultz, Peter G.. Dep. Chem., Univ. California,
Berkeley, CA, USA. Journal of the American Chemical Society (1990),
112(11), 4579-80.
In vitro suppression
of an amber mutation by a chemically aminoacylated transfer RNA
prepared by runoff transcription. Noren, Christopher J.; Anthony-Cahill,
Spencer J.; Suich, Daniel J.; Noren, Karen A.; Griffith, Michael
C.; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Nucleic Acids Research (1990), 18(1), 83-8.
New strategy
for selective protein cleavage. Hoyer, Denton; Cho, Ho; Schultz,
Peter G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Journal
of the American Chemical Society (1990), 112(8), 3249-50.
The use of
5'-phospho-2 deoxyribocytidylylriboadenosine as a facile route
to chemical aminoacylation of tRNA. Robertson, Stephanie A.;
Noren, Christopher J.; Anthony-Cahill, Spencer J.; Griffith, Michael
C.; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Nucleic Acids Research (1989), 17(23), 9649-60.
Design of catalytic
antibodies. Pollack, Scott J.; Nakayama, Grace R.; Schultz,
Peter G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Methods
in Enzymology (1989), 178 (Antibodies, Antigens, Mol. Mimicry),
551-68.
Site-specific
mutagenesis with unnatural amino acids. Anthony-Cahill S J;
Griffith M C; Noren C J; Suich D J; Schultz P. G.. Trends in Biochemical
Sciences (1989), 14(10), 400-3.
Generation
of a catalytic antibody by site-directed mutagenesis. Baldwin,
Enoch; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Science (Washington, D. C., 1883-) (1989), 245(4922),
1104-7.
Catalytic Antibodies. Schultz,
Peter G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Angewandte
Chemie, International Edition (1989), 28(10), 1283-95.
Sequence-selective
hydrolysis of duplex DNA by an oligonucleotide-directed nuclease. Corey,
David R.; Pei, Dehua; Schultz, Peter G.. Dep. Chem., Univ. California,
Berkeley, CA, USA. Journal of the American Chemical Society (1989),
111(22), 8523-5.
Stereospecific
hydrolysis of alkyl esters by antibodies. Pollack, Scott J.;
Hsiun, Paul; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Journal of the American Chemical Society (1989), 111(15),
5961-2.
Generation
of a catalytic sequence-specific hybrid DNase. Corey, David
R.; Pei, Dehua; Schultz, Peter G.. Dep. Chem., Univ. California,
Berkeley, CA, USA. Biochemistry (1989), 28(21), 8277-86.
Catalytic antibodies. Schultz,
Peter G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Accounts
of Chemical Research (1989), 22(8), 287-94.
A new strategy
for the generation of catalytic antibodies. Shokat, K. M.;
Leumann, C. J.; Sugasawara, R.; Schultz, P. G.. Dep. Chem., Univ.
California, Berkeley, CA, USA. Nature (London) (1989), 338(6212),
269-71.
Introduction
of a metal-dependent regulatory switch into an enzyme. Corey,
David R.; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Journal of Biological Chemistry (1989), 264(7), 3666-9.
1,1'-Carbonylbis(3-methylimidazolium)
triflate: an efficient reagent for aminoacylations. Saha, Ashis
K.; Rapoport, Henry; Schultz, Peter. Dep. Chem., Univ. California,
Berkeley, CA, USA. Journal of the American Chemical Society (1989),
111(13), 4856-9.
A general method
for site-specific incorporation of unnatural amino acids into proteins. Noren,
Christopher J.; Anthony-Cahill, Spencer J.; Griffith, Michael C.;
Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley, CA,
USA. Science (Washington, D. C., 1883-) (1989), 244(4901), 182-8.
Site-selective
cleavage of structured RNA by a staphylococcal nuclease-DNA hybrid. Zuckermann,
Ronald N.; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Proceedings of the National Academy of Sciences of the
United States of America (1989), 86(6), 1766-70.
A semisynthetic
catalytic antibody. Pollack, Scott J.; Schultz, Peter G.. Dep.
Chem., Univ. California, Berkeley, CA, USA. Journal of the American
Chemical Society (1989), 111(5), 1929-31.
Catalytic antibodies:
generation and characterization. Schultz, Peter G.; Jacobs,
Jeff W. Univ. California, Berkeley, CA, USA. Molecular
Structure and Energetics. (1988), 10(Environmental Influences
and Recognition in Enzyme Chemistry), 303-35.
Introduction
of nucleophiles and spectroscopic probes into antibody combining
sites. Pollack, Scott J.; Nakayama, Grace R.; Schultz, Peter
G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Science (Washington,
D. C., 1883-) (1988), 242(4881), 1038-40.
Antibody catalysis
in reverse micelles. Durfor, Charles N.; Bolin, Richard J.;
Sugasawara, Renee J.; Massey, Richard J.; Jacobs, Jeffrey; Schultz,
Peter G.. IGEN, Inc., Rockville, MD, USA. Journal of the American
Chemical Society (1988), 110(26), 8713-14.
An antibody
mediated redox reaction. Shokat, Kevan M.; Leumann, Christian
H.; Sugasawara, Renee; Schultz, Peter G.. Dep. Chem., Univ. California,
Berkeley, CA, USA. Angewandte Chemie, International Edition (1988),
27(9), 1172-74.
A hybrid sequence-selective
ribonuclease S. Zuckermann, Ronald N.; Schultz, Peter G.. Dep.
Chem., Univ. California, Berkeley, CA, USA. Journal of the American
Chemical Society (1988), 110(19), 6592-4.
Photosensitized
cleavage of a thymine dimer by an antibody. Cochran, Andrea
G.; Sugasawara, Renee; Schultz, Peter G.. Dep. Chem., Univ. California,
Berkeley, CA, USA. Journal of the American Chemical Society (1988),
110(23), 7888-90.
An antibody-catalyzed
Claisen rearrangement. Jackson, D. Y.; Jacobs, J. W.; Sugasawara,
R.; Reich, S. H.; Bartlett, P. A.; Schultz, Peter G.. Dep. Chem.,
Univ. California, Berkeley, CA, USA. Journal of the American Chemical
Society (1988), 110(14), 4841-2.
The interplay
between chemistry and biology in the design of enzymic catalysts. Schultz,
P. G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Science
(Washington, D. C., 1883-) (1988), 240(4851), 426-33.
Site-selective
cleavage of RNA by a hybrid enzyme. Zuckermann, Ronald N.;
Corey, David R.; Schultz, Peter G.. Dep. Chem., Univ. California,
Berkeley, CA, USA. Journal of the American Chemical Society (1988),
110(5), 1614-15.
Antibody catalysis
by transition state stabilization. Pollack, S. J.; Schultz,
P. G.. Dep. Chem., Univ. California, Berkeley, CA, USA. Cold Spring
Harbor Symposia on Quantitative Biology (1987), 52(Evolution of
Catalytic Function), 97-104.
Generation
of a hybrid sequence-specific single-stranded deoxyribonuclease. Corey,
D. R.; Schultz, P. G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Science (Washington, D. C., 1883-) (1987), 238(4832),
1401-3.
Efficient methods
for attachment of thiol specific probes to the 3'-ends of synthetic
oligodeoxyribonucleotides. Zuckermann, Ronald; Corey, David;
Schultz, Peter. Dep. Chem., Univ. California, Berkeley, CA, USA.
Nucleic Acids Research (1987), 15(13), 5305-21.
Catalytic antibodies. Jacobs,
Jeffrey; Schultz, Peter G.; Sugasawara, Renee; Powell, Michael. Dep.
Chem., Univ. California, Berkeley, CA, USA. Journal of the American
Chemical Society (1987), 109(7), 2174-6.
Selective chemical
catalysis by an antibody. Pollack, Scott J.; Jacobs, Jeffrey
W.; Schultz, Peter G.. Dep. Chem., Univ. California, Berkeley,
CA, USA. Science (Washington, D. C., 1883-) (1986), 234(4783),
1570-3.
Directed mutagenesis
of the redox-active disulfide in the flavoenzyme mercuric ion reductase. Schultz,
Peter G.; Au, Karin G.; Walsh, Christopher T. Dep. Chem., Massachusetts
Inst. Technol., Cambridge, MA, USA. Biochemistry (1985), 24(24),
6840-8.
DNA affinity
cleaving. Sequence specific cleavage of DNA by distamycin-EDTA ∙iron(II)
and EDTA-distamycin ∙iron(II). Taylor, John S.; Schultz,
Peter G.; Dervan, Peter B. Div. Chem. Chem. Eng., California Inst.
Technol., Pasadena, CA, USA. Tetrahedron (1984), 40(3), 457-65.
Distamycin
and penta-N-methylpyrrolecarboxamide binding sites on native DNA.
A comparison of methidiumpropyl-EDTA-iron(II) footprinting and
DNA affinity cleaving. Schultz, Peter G.; Dervan, Peter B.
Lab. Chem., California Inst. Technol., Pasadena, CA, USA. Journal
of Biomolecular Structure and Dynamics (1984), 1(5), 1133-47.
I. Ground and
excited state studies of persistent 1,1-diazenes. II. Design of
sequence specific DNA cleaving molecules. Schultz, Peter G..
California Inst. Technol., Pasadena, CA, USA. Avail. Univ. Microfilms
Int., Order No. DA8408535. (1983), 295 pp. From: Dissertaions Abstracts
International B 1984, 45(1), 198.
Sequence-specific
double-strand cleavage of DNA by penta-N-methylpyrrolecarboxamide-EDTA∙Fe(II). Schultz,
Peter G.; Dervan, Peter B. Div. Chem. Chem. Eng., California Inst.
Technol., Pasadena, CA, USA. Proceedings of the National Academy
of Sciences of the United States of America (1983), 80(22), 6834-7.
Sequence-specific
double-strand cleavage of DNA by bis(EDTA-distamycin.iron(II))
and EDTA-bis(distamycin).iron(II). Schultz, P. G.; Dervan,
P. B. Div. Chem. Chem. Eng., California Inst. Technol., Pasadena,
CA, USA. Journal of the American Chemical Society (1983), 105(26),
7748-50.
Design and
synthesis of a sequence-specific cleaving molecule - (Distamycin-EDTA0
Iron (II) Schultz, Peter G.; Taylor, J. S.; Dervan, P. B..
Journal of the American Chemical Society (1982) 104(24), 6861-83.
Photochemistry
of 1,1-diazenes. Direct and sensitized photolyses of N-(2,2,5,5-tetramethylpyrrolidyl)nitrene,
dl-N-(2,5-diethyl-2,5-dimethylpyrrolidyl)nitrene, and N-(2,2,6,6-tetramethylpiperidyl)nitrene. Schultz,
Peter G.; Dervan, Peter B. Div. Chem. Chem. Eng., California Inst.
Technol., Pasadena, CA, USA. Journal of the American Chemical Society
(1982), 104(24), 6660-8.
Direct studies
of 1,1-diazenes. Syntheses, infrared and electronic spectra, and
kinetics of the thermal decomposition of N-(2,2,6,6-tetramethylpiperidyl)nitrene
and N-(2,2,5,5-tetramethylpyrrolidyl)nitrene. Hinsberg, William
D., III; Schultz, Peter G.; Dervan, Peter B. Crellin Lab. Chem.,
California Inst. Technol., Pasadena, CA, USA. Journal of the American
Chemical Society (1982), 104(3), 766-73.
Photochemistry
of a 1,1-diazene, N-(2,2,5,5-tetramethylpyrrolidinyl)nitrene. Schultz,
Peter G.; Dervan, Peter B. Crellin Lab. Chem., California Inst.
Technol., Pasadena, CA, USA. Journal of the American Chemical Society
(1981), 103(6), 1563-4.
Synthesis and
direct spectroscopic observation of N-(2,2,5,5-tetramethylpyrrolidinyl)nitrene.
Comparison of five- and six-membered cyclic 1,1-dialkyldiazenes. Schultz,
Peter G.; Dervan, Peter B. Crellin Lab. Chem., California Inst.
Technol., Pasadena, CA, USA. Journal of the American Chemical Society
(1980), 102(2), 878-80.