UCI Authors RSS Feed

Erik Schwarz,Swamini Khurana,Arjun Chakrawal,Luciana Chavez Rodriguez,Johannes Wirsching,Thilo Streck,Stefano Manzoni,Martin Thullner,Holger Pagel

Spatial Control of Microbial Pesticide Degradation in Soil: A Model-Based Scenario Analysis

Tue, 27 Sep 2022
Microbial pesticide degraders are heterogeneously distributed in soil. Their spatial aggregation at the millimeter scale reduces the frequency of degrader-pesticide... Read more

PMID: 36166755

Trisha Saul,Teresa Rangel,Marietta V Sperry,Carrie Doyle,Jamie K Roney,Sherri Mendelson

Influence of a Formal Mentor on Hospital-Based Nurse Research Resources and Outcomes

Tue, 27 Sep 2022
Magnet® hospitals must conduct nursing research to maintain designation. Relationships between hospital research infrastructure, activities, and a designated nurse research... Read more

PMID: 36166632

Halle R Dimsdale-Zucker,Maria E Montchal,Zachariah M Reagh,Shao-Fang Wang,Laura A Libby,Charan Ranganath

Representations of Complex Contexts: A Role for Hippocampus

Tue, 27 Sep 2022
The hippocampus plays a critical role in supporting episodic memory, in large part by binding together experiences and items with... Read more

PMID: 36166300

Kevin K Ng,Jennifer A Prescher

Generalized Bioluminescent Platform To Observe and Track Cellular Interactions

Tue, 27 Sep 2022
Cell-to-cell communications are critical to biological processes ranging from embryonic development to cancer progression. Several imaging strategies have been developed... Read more

PMID: 36166258

Beth Haney

Acne: What primary care providers need to know

Tue, 27 Sep 2022
No abstract... Read more

PMID: 36165965

M G Rieger,C M Tallon,D R Perkins,K J Smith,M Stembridge,S Piombo,S Radom-Aizik,D M Cooper,P N Ainslie,A M McManus

Cardiopulmonary and cerebrovascular acclimatization in children and adults at 3800 meters

Tue, 27 Sep 2022
KEY POINTS: Children have different ventilatory and metabolic requirements than adults, which may present differently in the pulmonary and cerebral... Read more

PMID: 36165275

Hanyu Fan,Elianna S Frank,Douglas J Tobias,Vicki H Grassian

Interactions of limonene and carvone on titanium dioxide surfaces

Tue, 27 Sep 2022
Limonene, a monoterpene, found in cleaning products and air fresheners can interact with a variety of surfaces in indoor environments.... Read more

PMID: 36165087

Helen Ma,Joni Ricks-Oddie,Pankaj Gupta,Susan O'Brien,Wendy Cozen

IBCL-349 Veterans With Agent Orange Exposure Have a Shorter Latency From Exposure to Diagnosis of Indolent B-Cell Lymphoid Malignancies Compared to Unexposed Veterans

Tue, 27 Sep 2022
CONCLUSIONS: AO exposure was associated with a shorter latency from exposure to diagnosis of IBCL subtypes but was not associated... Read more

PMID: 36164109

Christopher R Flowers,John M Burke,Mirko Vukcevic,Susan Snodgrass,Kim Saverno,Mary Ann A Lumiqued,Haifaa Abdulhaq,Elizabeth Brem,Andrew Evens,Umar Farooq,Pierluigi Porcu,Mazyar Shadman

ABCL-051 realMIND: A Prospective, Multicenter, Observational Study of Patients With Relapsed/Refractory Diffuse Large B-Cell Lymphoma Starting Second/Third-Line Therapy and Not Receiving a Stem Cell Transplant

Tue, 27 Sep 2022
CONCLUSIONS: realMIND will characterize the R/R DLBCL patient journey with respect to treatment patterns, clinical and patient-reported outcomes. The study... Read more

PMID: 36164044

David Sallman,Monzr Al Malki,Adam Asch,Eunice Wang,Joseph Jurcic,Terrence Bradley,Ian Flinn,Daniel Pollyea,Suman Kambhampati,Tiffany Tanaka,Joshua Zeidner,Guillermo Garcia-Manero,Deepa Jeyakumar,Lin Gu,Anderson Tan,Mark Chao,Carol O'Hear,Indu Lal,Paresh Vyas,Naval Daver

MDS-445 Magrolimab In Combination With Azacitidine for Patients With Untreated Higher-Risk Myelodysplastic Syndromes (HR MDS): 5F9005 Phase 1b Study Results

Tue, 27 Sep 2022
CONCLUSIONS: Magrolimab+azacitidine was well tolerated, with promising efficacy in patients with untreated HR MDS, including those with TP53-mutated and -wild-type... Read more

PMID: 36163963

Jennifer R Brown,Peter Hillmen,Barbara Eichhorst,Nicole Lamanna,Susan O'Brien,Constantine S Tam,Lugui Qiu,Maciej Kazmierczak,Keshu Zhou,Martin Šimkovič,Jiri Mayer,Amanda Gillespie-Twardy,Mazyar Shadman,Alessandra Ferrajoli,Peter S Ganly,Robert Weinkove,Tommi Salmi,Kenneth Wu,William Novotny,Wojciech Jurczak

CLL-115 First Interim Analysis of ALPINE Study: Results of a Phase 3 Randomized Study of Zanubrutinib vs Ibrutinib in Patients With Relapsed/Refractory (R/R) Chronic Lymphocytic Leukemia/Small Lymphocytic Lymphoma (CLL/SLL)

Tue, 27 Sep 2022
CONCLUSIONS: In summary, this interim analysis showed zanubrutinib had a superior ORR, improved PFS, and lower AF rate compared to... Read more

PMID: 36163869

Naval Daver,Paresh Vyas,Suman Kambhampati,Monzr Al Malki,Richard Larson,Adam Asch,Gabriel Mannis,Wanxing Chai-Ho,Tiffany Tanaka,Terrence Bradley,Deepa Jeyakumar,Eunice Wang,Guan Xing,Mark Chao,Giri Ramsingh,Camille Renard,Indu Lal,Joshua Zeidner,David Sallman

AML-464 Tolerability and Efficacy of the First-In-Class Anti-CD47 Antibody Magrolimab Combined With Azacitidine in Frontline Patients With TP53-Mutated Acute Myeloid Leukemia (AML): Phase 1b Results

Tue, 27 Sep 2022
CONCLUSIONS: Magrolimab+azacitidine showed durable responses and encouraging overall survival in frontline patients with TP53-mutated AML unsuitable for intensive chemotherapy. A... Read more

PMID: 36163845

Naval Daver,Pau Montesinos,Ahmed Aribi,Giovanni Martinelli,Jessica K Altman,Eunice S Wang,Gail J Roboz,Patrick W Burke,Gianluca Gaidano,Roland B Walter,Xavier Thomas,Deepa Jeyakumar,Daniel J DeAngelo,Harry P Erba,Elisabetta Todisco,Kebede Begna,Anjali Advani,Lauris Gastaud,Adolfo de la Fuente,Antonio Curti,Lourdes M Mendez,Paresh Vyas,Nicolas Boissel,Norbert Vey,Christian Recher,Thomas Longval,Uwe Platzbecker,Silke Kapp-Schwörer,Christoph Schliemann,Marina Konopleva,Laura Torres,David A Sallman,Guido Marcucci,Giovanni Marconi,Hagop Kantarjian,Callum M Sloss,Karen E Malcolm,Patrick A Zweidler-McKay,Kendra Sweet

AML-262 Pivekimab Sunirine (PVEK, IMGN632) Triplet With Azacitidine and Venetoclax Shows Broad Activity in Adverse Genetic Subsets of Relapsed/Refractory Acute Myeloid Leukemia and Reduced Infusion-Related Reactions

Tue, 27 Sep 2022
CONCLUSIONS: The PVEK triplet with AZA+VEN demonstrates anti-leukemic activity across multiple high-risk genetic subsets of relapsed/refractory AML. Prophylactic steroids added... Read more

PMID: 36163801

Khodayar Goshtasbi,Arash Abiri,Sina Torabi,Benjamin F Bitner,Frank P K Hsu,Edward C Kuan

Association between metabolic syndrome and short-term adverse events in skull base surgery

Tue, 27 Sep 2022
No abstract... Read more

PMID: 36163698

Jenna L Merenstein,María M Corrada,Claudia H Kawas,Ilana J Bennett

White matter microstructural correlates of associative learning in the oldest-old

Tue, 27 Sep 2022
The ability to learn associations between events is critical for everyday functioning (e.g., decision making, social interactions) and has been... Read more

PMID: 36163584

Sahil Gulati,Krzysztof Palczewski

Structural view of G protein-coupled receptor signaling in the retinal rod outer segment

Mon, 26 Sep 2022
Visual phototransduction is the most extensively studied G protein-coupled receptor (GPCR) signaling pathway because of its quantifiable stimulus, non-redundancy of... Read more

PMID: 36163145

Steven J Barker,William C Wilson

Correspondence to: performance of the new SmartCardia wireless, wearable oximeter: a comparison with arterial SaO2 in healthy volunteers

Mon, 26 Sep 2022
In a recent publication in BMC Anesthesiology, Rincon, et al.present accuracy data for three pulse oximeters with sensors located at... Read more

PMID: 36163005

Arash Kheradvar,Gianni Pedrizzetti

State of energy of ventricular flow: A cause or the first indicator of adverse remodeling?

Mon, 26 Sep 2022
No abstract... Read more

PMID: 36162524

Zhen Han,Yi Lu,Yuyang Li,Rongzhen Wu,Zhen Huang

Strategy to combine two functional components: Efficient nano material development for iodine immobilization

Mon, 26 Sep 2022
The development of effective radioactive iodine adsorption materials from nuclear waste remains a significant challenge due to the drawbacks of... Read more

PMID: 36162517

Duyen Dinh-Dang,Abdullah Khafagy,Niklas Krause,Carisa Harris-Adamson

Assessment of cardiovascular load among hotel room cleaners

Mon, 26 Sep 2022
Hotel room cleaners are a vulnerable population at risk for cardiovascular disease. To evaluate their workload heart rate (HR), %... Read more

PMID: 36162273

Katelyn Laughon,Jason M Yu,Tianyu Zhu

Periodic Coupled-Cluster Green's Function for Photoemission Spectra of Realistic Solids

Mon, 26 Sep 2022
We present an efficient implementation of the coupled-cluster Green's function (CCGF) method for simulating photoemission spectra of periodic systems. We... Read more

PMID: 36162126

Hannah S Slocumb,Shaozhen Nie,Vy M Dong,Xiao-Hui Yang

Enantioselective Selenol-ene Using Rh-Hydride Catalysis

Mon, 26 Sep 2022
This study showcases the first enantioselective hydroselenation of styrenes. Organoselenium building blocks are accessed with selectivity for the branched isomer.... Read more

PMID: 36162123

Jiang Yao,Peter J Wagner,Yunpeng Xia,Gregory Czap,W Ho

Atomic-Scale Rectification and Inelastic Electron Tunneling Spectromicroscopy

Mon, 26 Sep 2022
The phenomenon of rectification describes the emergence of a DC current from the application of an oscillating voltage. Although the... Read more

PMID: 36162080

Andrea J Glenn,Jie Li,Kenneth Lo,David J A Jenkins,Beatrice A Boucher,Anthony J Hanley,Cyril W C Kendall,Aladdin H Shadyab,Lesley F Tinker,Steven D Chessler,Barbara V Howard,Simin Liu,John L Sievenpiper

The Portfolio Diet and Incident Type 2 Diabetes: Findings From the Women's Health Initiative Prospective Cohort Study

Mon, 26 Sep 2022
CONCLUSIONS: Greater adherence to the plant-predominant Portfolio, DASH, and Mediterranean diets was prospectively associated with lower risk of type 2... Read more

PMID: 36162007

Kaitlyn Burnell,Candice L Odgers

Trajectories of Perceived Technological Impairment and Psychological Distress in Adolescents

Mon, 26 Sep 2022
Fears that digital technologies harm adolescents' mental health abound; however, existing research is mixed. This study examined how perceived technological... Read more

PMID: 36161386

Ricky Camplain,Nicolette I Teufel-Shone,Luohua Jiang,Jennifer Chang,Spero M Manson

Change in physical activity, food choices and hemoglobin A1c among American Indians and Alaska Natives with type 2 diabetes

Mon, 26 Sep 2022
The prevalence of diabetes among American Indian and Alaska Native (AI/AN) adults is the highest of all United States racial/ethnic... Read more

PMID: 36161132

Rachael E Hokenson,Yasmine H Alam,Annabel K Short,Sunhee Jung,Cholsoon Jang,Tallie Z Baram

Sex-dependent effects of multiple acute concurrent stresses on memory: a role for hippocampal estrogens

Mon, 26 Sep 2022
Memory disruption commonly follows chronic stress, whereas acute stressors are generally benign. However, acute traumas such as mass shootings or... Read more

PMID: 36160685

Da Sun,Wenyu Sun,Song-Qi Gao,Jonathan Lehrer,Amirreza Naderi,Cheng Wei,Sangjoon Lee,Andrew L Schilb,Josef Scheidt,Ryan C Hall,Elias I Traboulsi,Krzysztof Palczewski,Zheng-Rong Lu

Effective gene therapy of Stargardt disease with PEG-ECO/pGRK1-ABCA4-S/MAR nanoparticles

Mon, 26 Sep 2022
Stargardt disease (STGD) is the most common form of inherited retinal genetic disorders and is often caused by mutations in... Read more

PMID: 36159595

Estefania Hernandez-Martin,Enrique Arguelles,Mark Liker,Aaron Robison,Terence D Sanger

Increased movement-related signals in both basal ganglia and cerebellar output pathways in two children with dystonia

Mon, 26 Sep 2022
The contribution of different brain regions to movement abnormalities in children with dystonia is unknown. Three awake subjects undergoing depth... Read more

PMID: 36158959

Jordan Harp,Lisa Koehl,Kathryn Van Pelt,Elizabeth Head,Gregory Jicha,William Robertson,Donita Lightner,Ira Lott,Frederick Schmitt

Primitive Reflexes and Dementia in Adults With Down Syndrome

Mon, 26 Sep 2022
BACKGROUND AND OBJECTIVES: To determine whether primitive reflexes serve as an indicator of dementia in adults with Down syndrome (DS),... Read more

PMID: 36157622

Akash H Patel,Balaji Natarajan,Ramdas G Pai

Current Management of Heart Failure with Preserved Ejection Fraction

Mon, 26 Sep 2022
Heart failure with preserved ejection fraction (HFpEF) encompasses nearly half of heart failure (HF) worldwide, and still remains a poor... Read more

PMID: 36157094

Mitchell R Farrell,Qiying Ye,Yiyan Xie,Jeanine Sandra D Esteban,Stephen V Mahler

Ventral pallidum GABA neurons bidirectionally control opioid relapse across rat behavioral models

Mon, 26 Sep 2022
Opioid addiction is a chronic, relapsing disorder. Whether addicted individuals are forced to abstain or they decide themselves to quit... Read more

PMID: 36156918

Mehwish Bhatti,Hayden Malone,Gabriel Hui,Ron D Frostig

Head Implants for the Neuroimaging of Awake, Head-Fixed Rats

Mon, 26 Sep 2022
Anesthetics, commonly used in preclinical and fundamental scientific research, have a depressive influence on the metabolic, neuronal, and vascular functions... Read more

PMID: 36155970

Miriam Bender,Joel Veenstra,Sarah Yoon

Improving interprofessional communication: Conceptualizing, operationalizing and testing a healthcare improvisation communication workshop

Mon, 26 Sep 2022
CONCLUSIONS: We have developed and tested a communication teaching modality with strong conceptual grounding and empirical evidence of its efficacy... Read more

PMID: 36155207

Yong Huang,Melissa D Pinto,Jessica L Borelli,Milad Asgari Mehrabadi,Heather L Abrahim,Nikil Dutt,Natalie Lambert,Erika L Nurmi,Rana Chakraborty,Amir M Rahmani,Charles A Downs

COVID Symptoms, Symptom Clusters, and Predictors for Becoming a Long-Hauler Looking for Clarity in the Haze of the Pandemic

Mon, 26 Sep 2022
Post-acute sequelae of SARS-CoV-2 (PASC) is defined as persistent symptoms after apparent recovery from acute COVID-19 infection, also known as... Read more

PMID: 36154716

Akhil Das,Kalon L Morgan,Faysal Yafi

Water Vapor Thermal Therapy: Minimally Invasive Treatment for Benign Prostatic Hyperplasia

Mon, 26 Sep 2022
Water vapor thermal therapy is a minimally invasive treatment for benign prostatic hyperplasia (BPH) that uses steam to ablate prostatic... Read more

PMID: 36154455

Fan-Gang Zeng

Celebrating the one millionth cochlear implant

Mon, 26 Sep 2022
Cochlear implants have been the most successful neural prosthesis, with one million users globally. Researchers used the source-filter model and... Read more

PMID: 36154048

Robyn G Langham,Kamyar Kalantar-Zadeh,Ann Bonner,Alessandro Balducci,Li-Li Hsiao,Latha A Kumaraswami,Paul Laffin,Vassilios Liakopoulos,Gamal Saadi,Ekamol Tantisattamo,Ifeoma Ulasi,Siu-Fai Lui,World Kidney Day Joint Steering Committee

Kidney health for all: Bridging the gap in kidney health education and literacy

Mon, 26 Sep 2022
The high burden of kidney disease, global disparities in kidney care, and poor outcomes of kidney failure bring a concomitant... Read more

PMID: 36153906

Collince J Omondi,Wilfred O Otambo,David Odongo,Kevin O Ochwedo,Antony Otieno,Shirley A Onyango,Pauline Orondo,Benyl M Ondeto,Ming-Chieh Lee,Daibin Zhong,James W Kazura,Andrew K Githeko,Guiyun Yan

Asymptomatic and submicroscopic Plasmodium infections in an area before and during integrated vector control in Homa Bay, western Kenya

Sat, 24 Sep 2022
CONCLUSIONS: These data suggest that two annual rounds of IRS integrated with LLINs significantly reduced the prevalence of Plasmodium parasitaemia,... Read more

PMID: 36153552

Tanya T Olmos-Ochoa,Tana M Luger,Anneka Oishi,Karen E Dyer,Annie Sumberg,Ismelda Canelo,Theodore K Gideonse,Ann Cheney,Elizabeth M Yano,Alison B Hamilton

Challenges to Engaging Women Veterans in Quality Improvement From Patient Care to Policy: Women's Health Managers' Perspectives

Sat, 24 Sep 2022
CONCLUSIONS: There may be unanticipated benefits to health care policy from engaging patients in QI, especially for patients with unique... Read more

PMID: 36153165

X Fu,Y Zhang,Y G Zhang,Y L Yin,S C Yan,Y Z Zhao,W Z Shen

Research and application of a new multilevel fuzzy comprehensive evaluation method for cold stress in dairy cows

Sat, 24 Sep 2022
Effective and comprehensive evaluation of cold stress is critical for healthy dairy cow breeding in the winter. Previous studies on... Read more

PMID: 36153158

Yingchao Xue,Chae Ho Lim,Maksim V Plikus,Mayumi Ito,George Cotsarelis,Luis A Garza

Wound-Induced Hair Neogenesis Model

Sat, 24 Sep 2022
Skin wounds in adult mammals typically heal with a fibrotic scar and fail to restore ectodermal appendages, such as hair... Read more

PMID: 36153062

Carey Y L Huh,Henri Leinonen,Taylor Nakayama,Julia R Tomasello,Jianye Zhang,Jack Zeitoun,John P Peach,Maximilian Halabi,Jianying Z Kiser,Krzysztof Palczewski,Philip D Kiser,Sunil P Gandhi

Retinoid therapy restores eye-specific cortical responses in adult mice with retinal degeneration

Sat, 24 Sep 2022
Despite the recent emergence of multiple cellular and molecular strategies to restore vision in retinal disorders, it remains unclear to... Read more

PMID: 36152631

Stella Garcia Colombarolli,Izabella Cristina Andrade Batista,Naiara Clemente Tavares,Eneida Santos de Oliveira,Camila Sales Nascimento,Philip Louis Felgner,Rafael Ramiro de Assis,Carlos Eduardo Calzavara-Silva

Peptide Microarrays for Flavivirus Diagnosis

Sat, 24 Sep 2022
Flavivirus are the most alarming prevalent viruses worldwide due to its vast impact on public health. Most early symptoms of... Read more

PMID: 36152289

Kwang-Mook Jung,Daniele Piomelli

Assay of Monoacylglycerol Lipase Activity

Sat, 24 Sep 2022
Monoacylglycerol lipase (MGL/MAGL/MGLL) is a serine hydrolase involved in the biological deactivation of the endocannabinoid 2-arachidonoyl-sn-glycerol (2-AG). 2-AG is the... Read more

PMID: 36152196

Kaoru Nashiro,Hyun Joo Yoo,Christine Cho,Jungwon Min,Tiantian Feng,Padideh Nasseri,Shelby L Bachman,Paul Lehrer,Julian F Thayer,Mara Mather

Correction: Effects of a Randomised Trial of 5-Week Heart Rate Variability Biofeedback Intervention on Cognitive Function: Possible Benefits for Inhibitory Control

Sat, 24 Sep 2022
No abstract... Read more

PMID: 36152080

Emily Kan,Nicholas Riano,Jordan Beardslee,Paul Frick,Laurence Steinberg,Elizabeth Cauffman

Race Differences in the Association Between Binge Drinking and Treatment Among First-Time Justice-System-Impacted Youth

Sat, 24 Sep 2022
CONCLUSION: Black youth who binge drink occasionally are less likely than White youth to receive alcohol treatment. The present findings... Read more

PMID: 36151735

Terry A Gates,Hengrui Cai,Yifei Hu,Xu Han,Emily Griffith,Landon Burgener,Ethan Hyland,Lindsay E Zanno

Estimating ancient biogeographic patterns with statistical model discrimination

Sat, 24 Sep 2022
The geographic ranges in which species live is a function of many factors underlying ecological and evolutionary contingencies. Observing the... Read more

PMID: 36151605

Melissa D Pinto,Charles A Downs,Yong Huang,Sarah A El-Azab,Nathan S Ramrakhiani,Anthony Barisano,Lu Yu,Kaitlyn Taylor,Alvaro Esperanca,Heather L Abrahim,Thomas Hughes,Maria Giraldo Herrera,Amir M Rahamani,Nikil Dutt,Rana Chakraborty,Christian Mendiola,Natalie Lambert

A distinct symptom pattern emerges for COVID-19 long-haul: a nationwide study

Fri, 23 Sep 2022
Long-haul COVID-19, also called post-acute sequelae of SARS-CoV-2 (PASC), is a new illness caused by SARS-CoV-2 infection and characterized by... Read more

PMID: 36151129

Yu-Huei Liu,Chun-Mei Hu,Yuan-Sheng Hsu,Wen-Hwa Lee

Interplays of glucose metabolism and KRAS mutation in pancreatic ductal adenocarcinoma

Fri, 23 Sep 2022
Pancreatic ductal adenocarcinoma (PDAC) is one of the most aggressive and deadliest cancer worldwide. The primary reasons for this are... Read more

PMID: 36151074